Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
about
Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognitionDistinct carboxy-termini confer divergent characteristics to the mitogen-activated protein kinase p38alpha and its splice isoform Mxi2Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimerProtein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complexRegulation of PRAK subcellular location by p38 MAP kinasesInhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expressionp38 MAPK in cardioprotection - are we there yet?Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-CellsZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF productionNovel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alphaGrb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factorDeficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cellsDecreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathwayGLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinaseRole of p38 MAP kinase in LPS-induced airway inflammation in the ratOverexpression of phospholipid hydroperoxide glutathione peroxidase modulates acetyl-CoA, 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activityRole of p38 MAP kinase in endothelial cell alignment induced by fluid shear stressNuclear localization of p38 MAPK in response to DNA damagep38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.Construction of a high-resolution 2.5-Mb transcript map of the human 6p21.2-6p21.3 region immediately centromeric of the major histocompatibility complex.A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation.Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cellsInhibition of the p38 kinase suppresses the proliferation of human ER-negative breast cancer cellsInflammatory mediators and stroke: new opportunities for novel therapeutics.PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.Induction of human NF-IL6beta by epidermal growth factor is mediated through the p38 signaling pathway and cAMP response element-binding protein activation in A431 cells.Stress signaling and the shaping of the mammary tissue in development and cancer.Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways.Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradationTherapeutic potential of anti-inflammatory drugs in focal stroke.Roles of p38 mitogen-activated protein kinase, NF-kappaB, and protein kinase C in proinflammatory cytokine mRNA expression by human peripheral blood leukocytes, monocytes, and neutrophils in response to Anaplasma phagocytophila.Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia.TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation.Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway.Perspective on the discovery and scientific impact of p38 MAP kinase.p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.Potential of anticytokine therapies in central nervous system ischaemia.
P2860
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P2860
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@ast
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@en
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@nl
type
label
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@ast
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@en
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@nl
prefLabel
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@ast
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@en
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@nl
P2093
P3181
P356
P1476
Novel homologues of CSBP/p38 M ...... bition by pyridinyl imidazoles
@en
P2093
P3181
P356
10.1006/BBRC.1997.6849
P407
P577
1997-06-27T00:00:00Z