p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. - Wikidata - wikimedia - TriplyDB

p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.

p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.

http://www.wikidata.org/entity/Q34372422

about

Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases Signaling effectors underlying pathologic growth and remodeling of the heart p38 MAPK in cardioprotection - are we there yet?The case for inhibiting p38 mitogen-activated protein kinase in heart failure Regulation of cell cycle and stress responses to hydrostatic pressure in fission yeast Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia p38 MAP kinases in the heart Context-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network Ligand-directed signalling at beta-adrenoceptors Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure Calpain protects the heart from hemodynamic stress.MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility.The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure.The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles.Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes P38α MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism.Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectives Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes.p38α MAPK is required for tooth morphogenesis and enamel secretion SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillation.Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction.The 14-3-3tau phosphoserine-binding protein is required for cardiomyocyte survival.Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation Exacerbation of autoimmune neuroinflammation by dietary sodium is genetically controlled and sex specific.Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection.Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6 Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse.Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.New frontiers in heart hypertrophy during pregnancy.Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation.

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p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.

http://www.wikidata.org/entity/Q34372422

description

2004 nî lūn-bûn

@nan

2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

p38alpha mitogen-activated pro ...... response to pressure overload.

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p38alpha mitogen-activated pro ...... response to pressure overload.

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p38alpha mitogen-activated pro ...... response to pressure overload.

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type

label

p38alpha mitogen-activated pro ...... response to pressure overload.

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p38alpha mitogen-activated pro ...... response to pressure overload.

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p38alpha mitogen-activated pro ...... response to pressure overload.

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prefLabel

p38alpha mitogen-activated pro ...... response to pressure overload.

@ast

p38alpha mitogen-activated pro ...... response to pressure overload.

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p38alpha mitogen-activated pro ...... response to pressure overload.

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MCB.24.24.10611-10620.2004

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Molecular and Cellular Biology

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p38alpha mitogen-activated pro ...... response to pressure overload

@en

P2093

Atsuko Nakai

http://www.w3.org/2001/XMLSchema#string

Gen Kondoh

http://www.w3.org/2001/XMLSchema#string

Junji Takeda

http://www.w3.org/2001/XMLSchema#string

Kazuhiko Nishida

http://www.w3.org/2001/XMLSchema#string

Kazunori Kashiwase

http://www.w3.org/2001/XMLSchema#string

Kenichi Hongo

http://www.w3.org/2001/XMLSchema#string

Kenneth R Chien

http://www.w3.org/2001/XMLSchema#string

Kinya Otsu

http://www.w3.org/2001/XMLSchema#string

Masatsugu Hori

http://www.w3.org/2001/XMLSchema#string

Masayuki Taniike

http://www.w3.org/2001/XMLSchema#string

P2860

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2

p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy

Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis

P304

10611-10620

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scholarly article

P356

10.1128/MCB.24.24.10611-10620.2004

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P433

24

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24

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Jun-ichi Miyazaki

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2004-12-01T00:00:00Z

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15572667

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533965

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