C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase - Wikidata - wikimedia - TriplyDB

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase

http://www.wikidata.org/entity/Q28251163

about

Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes AMPK in the brain: its roles in energy balance and neuroprotection The endocannabinoid system as an emerging target of pharmacotherapy From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase Structural basis for compound C inhibition of the human AMP-activated protein kinase α2 subunit kinase domain Regulation of peripheral metabolism by substrate partitioning in the brain.Optimization of energy-consuming pathways towards rapid growth in HPV-transformed cells Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation Luminal fructose inhibits rat intestinal sodium-phosphate cotransporter gene expression and phosphate uptake Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthood Applications of small molecule BMP inhibitors in physiology and disease.Central exercise action increases the AMPK and mTOR response to leptin Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation.Metabolic Impact of Light Phase-Restricted Fructose Consumption Is Linked to Changes in Hypothalamic AMPK Phosphorylation and Melatonin Production in Rats.AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects Quantitative RT-PCR and immunoblot analyses reveal acclimated A2 noradrenergic neuron substrate fuel transporter, glucokinase, phospho-AMPK, and dopamine-β-hydroxylase responses to hypoglycemia.To eat or not to eat: the effect of AICAR on food intake regulation in yellow-bellied marmots (Marmota flaviventris)A2 noradrenergic nerve cell metabolic transducer and nutrient transporter adaptation to hypoglycemia: impact of estrogen.Impact of metformin on reproductive tissues: an overview from gametogenesis to gestation Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats.Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding.Energy status determines hindbrain signal transduction pathway transcriptional reactivity to AMPK in the estradiol-treated ovariectomized female rat.Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes Up-regulation of AMP-activated protein kinase in cancer cell lines is mediated through c-Src activation.Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation.AMPK inhibition in health and disease.Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation Metformin-clinical pharmacology in PCOs.In the regulation of cytochrome P450 genes, phenobarbital targets LKB1 for necessary activation of AMP-activated protein kinase Age-related changes in AMP-activated protein kinase after stroke Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells.Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake.AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain

P2860

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P2860

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase

http://www.wikidata.org/entity/Q28251163

description

2004 nî lūn-bûn

@nan

2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

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2004年论文

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name

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@ast

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@en

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@nl

type

label

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@ast

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@en

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@nl

prefLabel

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@ast

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@en

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@nl

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P2860

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Journal of Biological Chemistry

P1476

C75, a fatty acid synthase inh ...... c AMP-activated protein kinase

@en

P2093

Eun-Kyoung Kim

http://www.w3.org/2001/XMLSchema#string

Francis P Kuhajda

http://www.w3.org/2001/XMLSchema#string

Gabriele V Ronnett

http://www.w3.org/2001/XMLSchema#string

Ian Miller

http://www.w3.org/2001/XMLSchema#string

Jill McFadden

http://www.w3.org/2001/XMLSchema#string

Leslie E Landree

http://www.w3.org/2001/XMLSchema#string

Michael Pinn

http://www.w3.org/2001/XMLSchema#string

Susan Aja

http://www.w3.org/2001/XMLSchema#string

Timothy H Moran

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

TSC2 mediates cellular energy response to control cell growth and survival

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

AMP-activated protein kinase plays a role in the control of food intake

Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

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19970-6

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scholarly article

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2439171

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10.1074/JBC.M402165200

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P433

19

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279

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2004-05-07T00:00:00Z

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15028725

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