Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival
about
The association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activityNetrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5BTemporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edemaVascular endothelial growth factor: an attractive target in the treatment of hypoxic/ischemic brain injuryThe roles of PIKE in tumorigenesisSrc regulates angiogenic factors and vascular permeability after focal cerebral ischemia-reperfusionFyn regulates adipogenesis by promoting PIKE-A/STAT5a interactionNicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growthRegulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications.Fyn promotes Th17 differentiation by regulating the kinetics of RORγt and Foxp3 expression.PIKE GTPase are phosphoinositide-3-kinase enhancers, suppressing programmed cell death.Arf GAPs and their interacting proteins.Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis.A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity.Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.PIKE is essential for oligodendroglia development and CNS myelination.A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia.What we have learnt about PIKE from the knockout mice.STAT5-Interacting Proteins: A Synopsis of Proteins that Regulate STAT5 Activity.Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity.Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activationMicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells.
P2860
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P2860
Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@ast
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@en
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@nl
type
label
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@ast
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@en
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@nl
prefLabel
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@ast
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@en
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@nl
P921
P356
P1476
Src-family tyrosine kinase fyn ...... ge and promoting cell survival
@en
P2888
P304
P356
10.1038/SJ.CDD.4402011
P407
P50
P577
2006-07-14T00:00:00Z