FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain
about
Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerasesIn situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6FKBP12 regulates the localization and processing of amyloid precursor protein in human cell linesCarbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptorThe 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptorFKBP12 binding modulates ryanodine receptor channel gatingLocalization of the 12.6-kDa FK506-binding protein (FKBP12.6) binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (ryanodine receptor)Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domainModulation of type-1 Ins(1,4,5)P3 receptor channels by the FK506-binding protein, FKBP12Transcriptome and biochemical analysis reveals that suppression of GPI-anchor synthesis leads to autophagy and possible necroptosis in Aspergillus fumigatusA novel role for the immunophilin FKBP52 in copper transportTGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytesWhat we don't know about the structure of ryanodine receptor calcium release channels.Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms.Regulation of Drosophila TRPL channels by immunophilin FKBP59.FK506 and the role of the immunophilin FKBP-52 in nerve regeneration.The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication.Cyclophilins and their possible role in the stress response.Inositol trisphosphate receptor Ca2+ release channels.Calcium transport across the sarcoplasmic reticulum: structure and function of Ca2+-ATPase and the ryanodine receptor.Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress by increasing its transduction efficiency.Immunophilins: switched on protein binding domains?The conserved sites for the FK506-binding proteins in ryanodine receptors and inositol 1,4,5-trisphosphate receptors are structurally and functionally different.Activation and inhibition of skeletal RyR channels by a part of the skeletal DHPR II-III loop: effects of DHPR Ser687 and FKBP12.Microbial peptidyl-prolyl cis/trans isomerases (PPIases): virulence factors and potential alternative drug targets.Neuroimmunophilins: novel neuroprotective and neuroregenerative targets.Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules.Unzipping ion channels.Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes.Transforming growth factor beta in cardiovascular development and function.Neurochemical targets and behavioral effects of organohalogen compounds: an update.Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes.N-terminal and central segments of the type 1 ryanodine receptor mediate its interaction with FK506-binding proteinsMolecular mechanism of ventricular trabeculation/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC)Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants.Ryanodine receptor-mediated arrhythmias and sudden cardiac death.Analysis of ventricular hypertrabeculation and noncompaction using genetically engineered mouse models.
P2860
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P2860
FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@ast
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@en
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@nl
type
label
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@ast
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@en
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@nl
prefLabel
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@ast
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@en
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@nl
P2093
P2860
P356
P1476
FKBP12 binds the inositol 1,4, ...... urin to this FK506-like domain
@en
P2093
A M Cameron
D J Livingston
F C Nucifora
R A Aldape
P2860
P304
P356
10.1074/JBC.272.44.27582
P407
P577
1997-10-31T00:00:00Z