Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II
about
Bioflavonoids as poisons of human topoisomerase II alpha and II betaDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementDietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaProteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2{middle dot}DNA and Top2{middle dot}RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor functionPlants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggabilityGenistein-supplemented diet decreases malaria liver infection in mice and constitutes a potential prophylactic strategyGenome-wide characterisation of the binding repertoire of small molecule drugs.The expression of sphingosine kinase-1 in head and neck carcinomaIsoflavones, their Glycosides and Glycoconjugates. Synthesis and Biological Activity.A Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer CellsDifferential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces.Acute effects of 17 β-estradiol and genistein on insulin sensitivity and spatial memory in aged ovariectomized female ratsCured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study.Effect of soy isoflavones on the growth of human breast tumors: findings from preclinical studiesPhytoestrogens: epidemiology and a possible role in cancer protection.Phytoestrogens are partial estrogen agonists in the adult male mouse.Dietary Estrogens Act through Estrogen Receptor-Mediated Processes and Show No Antiestrogenicity in Cultured Breast Cancer Cells.Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer.Flavonoids: A versatile source of anticancer drugs.H-Ras oncogene counteracts the growth-inhibitory effect of genistein in T24 bladder carcinoma cells.Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative.Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway.Role of metabolism in the effects of genistein and its phase II conjugates on the growth of human breast cell lines.Cytotoxic activity of genistein-8-C-glucoside form Lupinus luteus L. and genistein against human SK-OV-3 ovarian carcinoma cell line.Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects.Noncatalytic inhibition of cyclic nucleotide-gated channels by tyrosine kinase induced by genistein.Inhibition of growth and induction of differentiation of metastatic melanoma cells in vitro by genistein: chemosensitivity is regulated by cellular p53Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53.Stimulatory and inhibitory effects of genistein on human uterine leiomyoma cell proliferation are influenced by the concentrationBiological clues to potent DNA-damaging activities in food and flavoring.The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study.Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikoninEvaluation of synthetic isoflavones on cell proliferation, estrogen receptor binding affinity, and apoptosis in human breast cancer cellsAnti-diabetic functions of soy isoflavone genistein: mechanisms underlying its effects on pancreatic β-cell function.Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trialContinuous in vitro exposure to low-dose genistein induces genomic instability in breast epithelial cellsThe DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingA High Concentration of Genistein Induces Cell Death in Human Uterine Leiomyoma Cells by Autophagy.
P2860
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P2860
Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II
description
1989 nî lūn-bûn
@nan
1989 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@ast
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@en
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@nl
type
label
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@ast
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@en
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@nl
prefLabel
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@ast
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@en
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@nl
P2093
P3181
P1433
P1476
Inhibitory effects of the tyro ...... mammalian DNA topoisomerase II
@en
P2093
A Jacquemin-Sablon
A K Larsen
C Linassier
J B Le Pecq
J M Saucier
J Markovits
P304
P3181
P407
P577
1989-09-15T00:00:00Z