Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.
about
Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plantsCurcumin and genistein: the combined effects on disease-associated CFTR mutants and their clinical implicationsSmall molecule correctors of F508del-CFTR discovered by structure-based virtual screeningPharmacological Correctors of Mutant CFTR Mistrafficking.Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.A novel approach to recovery of function of mutant proteins by slowing down translation.Application of high-resolution single-channel recording to functional studies of cystic fibrosis mutants.Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.Colloidal drug formulations can explain "bell-shaped" concentration-response curves.Managing the underlying cause of cystic fibrosis: a future role for potentiators and correctors.Two Small Molecules Restore Stability to a Subpopulation of the Cystic Fibrosis Transmembrane Conductance Regulator with the Predominant Disease-causing Mutation.CFTR pharmacology.Influence of cell background on pharmacological rescue of mutant CFTR.Potentiation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl- currents by the chemical solvent tetrahydrofuran.Differential sensitivity of the cystic fibrosis (CF)-associated mutants G551D and G1349D to potentiators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel.A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein.Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH.Curcumin and genistein additively potentiate G551D-CFTR.CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics.Direct sensing of intracellular pH by the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channelDesigner pharmacotherapy for the treatment of cystic fibrosis: commentary on Zegarra-Moran et al.Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule.Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokinesGelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways
P2860
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P2860
Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Correction of G551D-CFTR trans ...... tein but not by CPX or MPB-07.
@en
type
label
Correction of G551D-CFTR trans ...... tein but not by CPX or MPB-07.
@en
prefLabel
Correction of G551D-CFTR trans ...... tein but not by CPX or MPB-07.
@en
P2093
P2860
P50
P356
P1476
Correction of G551D-CFTR trans ...... stein but not by CPX or MPB-07
@en
P2093
Chiara Folli
Emanuela Caci
Jean-Michel Vierfond
Leila Romio
Olga Zegarra-Moran
Yvette Mettey
P2860
P304
P356
10.1038/SJ.BJP.0704882
P407
P577
2002-10-01T00:00:00Z