Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum
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Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagyRole of Nrf1 in antioxidant response element-mediated gene expression and beyondThe C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expressionTranscription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymesDual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanismsThe Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysisThe Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxiaTranscription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cellsGlycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genesKeap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2Stress-activated cap'n'collar transcription factors in aging and human diseaseHrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosisSmall molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agentsDietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: A reviewA small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophyMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseTranscription factor Nrf1 is negatively regulated by its O-GlcNAcylation statusCharacterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genesMCRS2 represses the transactivation activities of Nrf1.Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.Mechanisms and functions of Nrf2 signaling in Drosophila.Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome.NFE2L3 (NRF3): the Cinderella of the Cap'n'Collar transcription factors.NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genesNatural antioxidants exhibit chemopreventive characteristics through the regulation of CNC b-Zip transcription factors in estrogen-induced breast carcinogenesisEndoplasmic reticulum association and N-linked glycosylation of the human Nrf3 transcription factor.The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence.SKN-1/Nrf, a new unfolded protein response factor?Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domainsThe selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expressionTALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cellsNrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healingThe role of endothelial mechanosensitive genes in atherosclerosis and omics approaches.SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compThe membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity.Molecular mechanisms of Nrf2-mediated antioxidant responseThe generation, detection, and effects of reactive drug metabolites.
P2860
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P2860
Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@ast
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@en
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@nl
type
label
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@ast
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@en
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@nl
prefLabel
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@ast
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@en
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@nl
P2860
P3181
P356
P1433
P1476
Negative regulation of the Nrf ...... d to the endoplasmic reticulum
@en
P2093
Dorothy H Crouch
Masayuki Yamamoto
P2860
P304
P3181
P356
10.1042/BJ20060725
P407
P577
2006-11-01T00:00:00Z