Role of mammalian Mre11 in classical and alternative nonhomologous end joining
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DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formationKu regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsMutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repairDNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cellsLocalization of BRCA1 protein in breast cancer tissue and cell lines with mutationsDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsRobust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)Telomere dysfunction and chromosome instabilityDNA Damage Response in Hematopoietic Stem Cell AgeingFunctional Role of NBS1 in Radiation Damage Response and Translesion DNA SynthesisRNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break RepairNucleases in homologous recombination as targets for cancer therapyThe convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancerCausal link between microsatellite instability and hMRE11 dysfunction in human cancersBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?DNA Polymerase θ: A Unique Multifunctional End-Joining MachineNoncanonical views of homology-directed DNA repairMicrohomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choiceMRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage ResponseThe response to and repair of RAG-mediated DNA double-strand breaksHomology and enzymatic requirements of microhomology-dependent alternative end joiningTerminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteinsDouble strand break repair functions of histone H2AXDual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.Autophosphorylation and ATM activation: additional sites add to the complexity.WRN regulates pathway choice between classical and alternative non-homologous end joiningLimiting the persistence of a chromosome break diminishes its mutagenic potential.Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.Generation and repair of AID-initiated DNA lesions in B lymphocytes.A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.RAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapyATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex.Dicentric breakage at telomere fusions.
P2860
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P2860
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
description
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
scientific article (publication date: August 2009)
@en
vedecký článok (publikovaný 2009-08)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd in 2009-08)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в серпні 2009
@uk
مقالة علمية (نشرت في أغسطس 2009)
@ar
name
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@ast
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@en
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@nl
type
label
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@ast
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@en
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@nl
prefLabel
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@ast
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@en
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@nl
P2093
P2860
P3181
P356
P1476
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
@en
P2093
Anyong Xie
Ralph Scully
P2860
P2888
P3181
P356
10.1038/NSMB.1640
P407
P577
2009-08-01T00:00:00Z