Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways
about
The functional significance of microRNA-145 in prostate cancerMechanism of Action and Applications of Interleukin 24 in ImmunotherapyA novel splicing variant of mouse interleukin (IL)-24 antagonizes IL-24-induced apoptosisRecombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.Tumour suppressor function of MDA-7/IL-24 in human breast cancerEnhanced apoptosis-inducing function of MDA-7/IL-24 RGD mutant via the increased adhesion to tumor cells.The development of MDA-7/IL-24 as a cancer therapeuticA serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokinemda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokineMDA-7/IL-24: multifunctional cancer killing cytokineAdenovirus as vehicle for anticancer genetic immunotherapy.Gene delivery and gene therapy of prostate cancer.Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?IL-24: a classic cytokine and/or a potential cure for cancer?Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells.E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice.HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1.Naturally occurring, tumor-specific, therapeutic proteins.Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities.Cell-penetrating and endoplasmic reticulum-locating TAT-IL-24-KDEL fusion protein induces tumor apoptosis.Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activityIL-24 sensitizes tumor cells to TLR3-mediated apoptosisInhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo.Enhanced antitumor activity by a selective conditionally replicating adenovirus combining with MDA-7/interleukin-24 for B-lymphoblastic leukemia via induction of apoptosis.eIF2α Phosphorylation Mediates IL24-Induced Apoptosis through Inhibition of Translation.IL-24 inhibits the growth of hepatoma cells in vivo
P2860
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P2860
Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@ast
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@en
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@nl
type
label
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@ast
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@en
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@nl
prefLabel
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@ast
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@en
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@nl
P2093
P3181
P1433
P1476
Melanoma differentiation assoc ...... tory and nonsecretory pathways
@en
P2093
Aaron Randolph
Heng-tong Choo
Irina V Lebedeva
Kristoffer Valerie
Moira Sauane
Paul B Fisher
Rahul V Gopalkrishnan
Zao-zhong Su
P304
P3181
P356
10.1158/0008-5472.CAN-04-0200
P407
P50
P577
2004-05-01T00:00:00Z