about
Gambogenic acid kills lung cancer cells through aberrant autophagyCharacterization of the canine mda-7 gene, transcripts and expression patterns.Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironmentmda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Insulin-like growth factor binding protein-3 mediates interleukin-24-induced apoptosis through inhibition of the mTOR pathway in prostate cancer.MDA-7/IL-24: multifunctional cancer killing cytokineHistone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells.Conditionally replicating adenoviruses carrying mda-7/IL-24 for cancer therapy.Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities.A conditionally replicating adenovirus expressing IL-24 acts synergistically with temozolomide to enhance apoptosis in melanoma cells in vitro.Cell-penetrating and endoplasmic reticulum-locating TAT-IL-24-KDEL fusion protein induces tumor apoptosis.MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis.Optimisation of the mRNA secondary structure to improve the expression of interleukin-24 (IL-24) in Escherichia coli.Inhibitory effect of melanoma differentiation associated gene-7/interleukin-24 on invasion in vitro of human melanoma cancer cells.Cancer targeting gene-viro-therapy for pancreatic cancer using oncolytic adenovirus ZD55-IL-24 in immune-competent mice.Adenovirus arming human IL-24 inhibits neuroblastoma cell proliferation in vitro and xenograft tumor growth in vivo.Reversal effect of melanoma differentiation associated gene-7/interleukin-24 on multidrug resistance in human hepatocellular carcinoma cells.MDA-7/IL-24 inhibits cell survival by inducing apoptosis in nasopharyngeal carcinoma.Interleukin-24 inhibits osteosarcoma cell migration and invasion via the JNK/c-Jun signaling pathways.Biological nanoparticles carrying the Hmda-7 gene are effective in inhibiting pancreatic cancer in vitro and in vivo.A dual-regulated oncolytic adenovirus expressing interleukin-24 sensitizes melanoma cells to temozolomide via the induction of apoptosis.The potential of virus-based gene therapies for treatment of metastatic kidney cancer.Cancer Terminator Viruses (CTV): A Better Solution for Viral-Based Therapy of Cancer.Soluble expression, rapid purification, and characterization of human interleukin-24 (IL-24) using a MBP-SUMO dual fusion system in Escherichia coli.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The development of MDA-7/IL-24 as a cancer therapeutic
@ast
The development of MDA-7/IL-24 as a cancer therapeutic
@en
The development of MDA-7/IL-24 as a cancer therapeutic
@nl
type
label
The development of MDA-7/IL-24 as a cancer therapeutic
@ast
The development of MDA-7/IL-24 as a cancer therapeutic
@en
The development of MDA-7/IL-24 as a cancer therapeutic
@nl
prefLabel
The development of MDA-7/IL-24 as a cancer therapeutic
@ast
The development of MDA-7/IL-24 as a cancer therapeutic
@en
The development of MDA-7/IL-24 as a cancer therapeutic
@nl
P2093
P2860
P1476
The development of MDA-7/IL-24 as a cancer therapeutic
@en
P2093
Adly Yacoub
Devanand Sarkar
Harold F Young
Hossein A Hamed
Irina V Lebedeva
Luni Emdad
Maciej S Lesniak
Margaret A Park
Mohamed Rahmani
Moira Sauane
P2860
P304
P356
10.1016/J.PHARMTHERA.2010.08.001
P577
2010-08-21T00:00:00Z