Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345
about
Delineation of the peptide binding site of the human galanin receptorEvidence for a direct interaction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptorBiophysical methods to study ligand-receptor interactions of neuropeptide YFluorescence spectroscopy of jet-cooled chiral (+/-)-indan-1-ol and its cluster with (+/-)-methyl- and ethyl-lactate.Identification of an adenosine receptor domain specifically involved in binding of 5'-substituted adenosine agonists.Mapping substance P binding sites on the neurokinin-1 receptor using genetic incorporation of a photoreactive amino acid.Molecular Architecture of G Protein-Coupled Receptors.Delineation of a region in the B2 bradykinin receptor that is essential for high-affinity agonist binding.Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.Tyr-129 is important to the peptide ligand affinity and selectivity of human endothelin type A receptor.Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmissionTwo nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors.Probing weakly polar interactions in cytochrome cMolecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.Two amino acids, located in transmembrane domains VI and VII, determine the selectivity of the peptide agonist SMS 201-995 for the SSTR2 somatostatin receptorActivation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.Modeling and docking the endothelin G-protein-coupled receptor.Molecular characterization of the substance P*neurokinin-1 receptor complex: development of an experimentally based model.Connectivity and orientation of the seven helical bundle in the tachykinin NK-1 receptor probed by zinc site engineering.Mutational analysis of neurokinin receptor function.Small molecule ligands for oxytocin and vasopressin receptors.Separable binding sites for the natural agonist endothelin-1 and the non-peptide antagonist bosentan on human endothelin-A receptors.Aspartate mutation distinguishes ETA but not ETB receptor subtype-selective ligand binding while abolishing phospholipase C activation in both receptors.Mapping peptide-binding domains of the substance P (NK-1) receptor from P388D1 cells with photolabile agonists.High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system.Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors.How receptor mutagenesis may confirm or confuse receptor classification.Conserved HisVI-17 of the NK-1 receptor is involved in binding of non-peptide antagonists but not substance P.Molecular recognition of peptide and non-peptide ligands by the extracellular domains of neurohypophysial hormone receptors.Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor.Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B.Mutagenesis and modeling of the neurotensin receptor NTR1. Identification of residues that are critical for binding SR 48692, a nonpeptide neurotensin antagonist.Shared determinants of receptor binding for subtype selective, and dual endothelin-angiotensin antagonists on the AT1 angiotensin II receptor.UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation.Construction of a high affinity zinc switch in the kappa-opioid receptor.Role of aromatic transmembrane residues of the delta-opioid receptor in ligand recognition.Probing the binding pocket and endocytosis of a G protein-coupled receptor in live cells reported by a spin-labeled substance P agonist.An ab initio theoretical prediction: an antiaromatic ring pi-dihydrogen bond accompanied by two secondary interactions in a "wheel with a pair of pedals" shaped complex FH . . . C4H4 . . . HF.Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor.
P2860
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P2860
Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@ast
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@en
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@nl
type
label
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@ast
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@en
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@nl
prefLabel
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@ast
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@en
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@nl
P2093
P356
P1433
P1476
Amino-aromatic interaction bet ...... okinin-1 receptor and CP 96345
@en
P2093
P2888
P356
10.1038/362350A0
P407
P577
1993-03-25T00:00:00Z
P6179
1014721773