TGF-beta-activated kinase 1 stimulates NF-kappa B activation by an NF-kappa B-inducing kinase-independent mechanism
about
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathwayTumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathwayReceptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1Discovery of mammalian genes that participate in virus infectionMutations in MAP3K7 that Alter the Activity of the TAK1 Signaling Complex Cause Frontometaphyseal DysplasiaASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interactionWnt activates the Tak1/Nemo-like kinase pathwayMutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responsesTAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaBArsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1.Mullerian-inhibiting substance regulates NF-kappa B signaling in the prostate in vitro and in vivo.TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila developmentMemory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLLTargeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer.Transcriptional networks inferred from molecular signatures of breast cancerRole of transforming growth factor-beta in cancer progression.Alternative splicing in the NF-kappaB signaling pathway.Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses.NF-κB inducing kinase: a key regulator in the immune system and in cancerTranscriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: a negative role for NF-kappaB.Recent Pathophysiological Aspects of Peyronie's Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment-Literature Review.Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts.Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors.Signaling by the Mpl receptor involves IKK and NF-kappaB.Enhancement of lipopolysaccharide-stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirus-mediated inhibition of inhibitory kappa B kinase signalling.POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κB pathway.Dominant-negative TAK1 induces c-Myc and G(0) exit in liver.Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling.TAK1 plays a major role in growth factor-induced phenotypic modulation of airway smooth muscle.Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells.Structure-guided development of covalent TAK1 inhibitors.Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma.Functional Interactions of Transforming Growth Factor β-activated Kinase 1 with IκB Kinases to Stimulate NF-κB ActivationCurcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects Through Suppression of TAK1-NF-κB Pathway
P2860
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P2860
TGF-beta-activated kinase 1 stimulates NF-kappa B activation by an NF-kappa B-inducing kinase-independent mechanism
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@ast
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@en
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@nl
type
label
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@ast
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@en
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@nl
prefLabel
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@ast
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@en
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@nl
P2093
P356
P1476
TGF-beta-activated kinase 1 st ...... g kinase-independent mechanism
@en
P2093
P304
P356
10.1006/BBRC.1998.8124
P407
P577
1998-02-01T00:00:00Z