Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
about
Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activitiesRepression by Ikaros and Aiolos is mediated through histone deacetylase complexesCOUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding proteinExpression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemiaIkaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activityEos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous systemIkaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repressionUnconventional potentiation of gene expression by IkarosA molecular dissection of the repression circuitry of IkarosThe Ikaros family protein Eos associates with C-terminal-binding protein corepressorsIkaros SUMOylation: switching out of repressionExpression of a unique helios isoform in human leukemia cells.Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene.How B cells influence bone biology in health and diseaseIkaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.Regulation of lineage commitment during lymphocyte development.Ikaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virusHaematopoietic cell-fate decisions, chromatin regulation and ikaros.Critical function of Ikaros in controlling Aiolos gene expression.Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells.Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cellsThe combined expression patterns of Ikaros isoforms characterize different hematological tumor subtypesA lack of association between the IKZF2 rs12619285 polymorphism and coronary heart disease.Ikaros is required for plasmacytoid dendritic cell differentiation.Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons.Transcriptional networks in developing and mature B cells.Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.Defects in hemopoietic stem cell activity in Ikaros mutant mice.Helios Controls a Limited Subset of Regulatory T Cell FunctionsThe Immune Fulcrum: Regulatory T Cells Tip the Balance Between Pro- and Anti-inflammatory Outcomes upon InfectionIkaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.Transcriptional regulation of the Ikzf1 locus.Variations in mRNA and protein levels of Ikaros family members in pediatric T cell acute lymphoblastic leukemia.A central role for induced regulatory T cells in tolerance induction in experimental colitis.A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.The genomic landscape of hypodiploid acute lymphoblastic leukemia.tTregs, pTregs, and iTregs: similarities and differences.Zinc finger structure-function in Ikaros Marvin A Payne.
P2860
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P2860
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@ast
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@en
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@nl
type
label
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@ast
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@en
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@nl
prefLabel
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@ast
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@en
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@nl
P2093
P3181
P1433
P1476
Helios, a novel dimerization p ...... iest hematopoietic progenitors
@en
P2093
B A Morgan
C M Kelley
J Koipally
K Georgopoulos
P304
P3181
P356
10.1016/S0960-9822(98)70202-7
P407
P577
1998-04-23T00:00:00Z