MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection - Wikidata - wikimedia - TriplyDB

MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection

MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection

http://www.wikidata.org/entity/Q28270572

about

The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy Effect of CDR3 Sequences and Distal V Gene Residues in Regulating TCR-MHC Contacts and Ligand Specificity T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex αβ T cell receptors as predictors of health and disease Reconciling views on T cell receptor germline bias for MHC Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3 Lck availability during thymic selection determines the recognition specificity of the T cell repertoire T cell receptor bias for MHC: co-evolution or co-receptors?How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire Revisiting thymic positive selection and the mature T cell repertoire for antigen.Gamma delta T cells recognize haptens and mount a hapten-specific response.A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction Clinical applications of gamma delta T cells with multivalent immunity.How many TCR clonotypes does a body maintain?Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.Revealing the TCR bias for MHC molecules Functional evidence for TCR-intrinsic specificity for MHCII.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system αβ T cell receptor germline CDR regions moderate contact with MHC ligands and regulate peptide cross-reactivity Soluble γc cytokine receptor suppresses IL-15 signaling and impairs iNKT cell development in the thymus Duality of the murine CD8 compartment.The T cell antigen receptor: the Swiss army knife of the immune system.Thoughts on Positive Selection in Thymus.Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR.How an alloreactive T-cell receptor achieves peptide and MHC specificity.Bacterial clearance reverses a skewed T-cell repertoire induced by Salmonella infection.Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors.

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MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection

http://www.wikidata.org/entity/Q28270572

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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MHC restriction is imposed on ...... eptors during thymic selection

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J.IT.2012.05.006

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Trends in Immunology

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MHC restriction is imposed on ...... eptors during thymic selection

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P2093

Alfred Singer

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Anastasia N Tikhonova

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François Van Laethem

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P2860

Interaction between CD4 and class II MHC molecules mediates cell adhesion

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers

Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4

Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection

αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities

The molecular basis of TCR germline bias for MHC is surprisingly simple

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

TCR-MHC docking orientation: natural selection, or thymic selection?

How TCRs bind MHCs, peptides, and coreceptors

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437-41

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scholarly article

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2588444

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10.1016/J.IT.2012.05.006

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9

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33

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2012-09-01T00:00:00Z

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3427466

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