Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130 - Wikidata - wikimedia - TriplyDB

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

http://www.wikidata.org/entity/Q24564280

about

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation The leptin receptor promoter controls expression of a second distinct protein Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region Functional regions of the mouse interleukin-10 receptor cytoplasmic domain Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells Mitochondrial Stat3, the Need for Design Thinking Metabolic actions of Rho-kinase in periphery and brain Mapping of a region within the N terminus of Jak1 involved in cytokine receptor interaction Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors The conserved box 1 motif of cytokine receptors is required for association with JAK kinases Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders The Hyper-IgE Syndromes: Lessons in Nature, From Bench to Bedside The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130 n-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generation Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction Evolution of Class I cytokine receptors Central exercise action increases the AMPK and mTOR response to leptin Establishment of a congenital amegakaryocytic thrombocytopenia model and a thrombocyte-specific reporter line in zebrafish.Neuroprotection of interleukin-6 against NMDA-induced apoptosis and its signal-transduction mechanisms.Signaling through Gp130: toward a general scenario of cytokine action.Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy The amino terminus of the fourth cytoplasmic loop of rhodopsin modulates rhodopsin-transducin interaction.Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.Proliferation of immature myeloma cells by interleukin-6 is associated with CD45 expression in human multiple myeloma.Janus kinases: components of multiple signaling pathways.Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation.Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.Physiological and molecular determinants of embryo implantation Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6.The paradigm of IL-6: from basic science to medicine

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P2860

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

http://www.wikidata.org/entity/Q24564280

description

1994 nî lūn-bûn

@nan

1994 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի մարտին հրատարակված գիտական հոդված

@hy

1994年の論文

@ja

1994年論文

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1994年論文

@zh-hant

1994年論文

@zh-hk

1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

name

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@ast

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@en

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@nl

type

label

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@ast

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@en

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@nl

prefLabel

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@ast

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@en

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

@en

P2093

B A Witthuhn

http://www.w3.org/2001/XMLSchema#string

J N Ihle

http://www.w3.org/2001/XMLSchema#string

K Yasukawa

http://www.w3.org/2001/XMLSchema#string

K Yoshida

http://www.w3.org/2001/XMLSchema#string

M Narazaki

http://www.w3.org/2001/XMLSchema#string

O Silvennoinen

http://www.w3.org/2001/XMLSchema#string

T Kishimoto

http://www.w3.org/2001/XMLSchema#string

T Taga

http://www.w3.org/2001/XMLSchema#string

P2860

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

Molecular cloning and expression of an IL-6 signal transducer, gp130

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

Signal transduction by receptors with tyrosine kinase activity

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

P304

2285-9

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1073/PNAS.91.6.2285

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P433

6

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P478

91

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1994-03-15T00:00:00Z

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15065643

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8134389

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P932

43355

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