I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment
about
Mutations altering the cleavage specificity of a homing endonucleaseStructural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factorHoming endonuclease I-CreI derivatives with novel DNA target specificitiesHoming endonuclease mediated gene targeting in Anopheles gambiae cells and embryosA functional analysis of the spacer of V(D)J recombination signal sequencesI-ApeKI [corrected]: a novel intron-encoded LAGLIDADG homing endonuclease from the archaeon, Aeropyrum pernix K1Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradationGeneration of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins5'-Cytosine-Phosphoguanine (CpG) Methylation Impacts the Activity of Natural and Engineered MeganucleasesTapping natural reservoirs of homing endonucleases for targeted gene modificationHoming endonucleases: structural and functional insight into the catalysts of intron/intein mobilityHighly Efficient Sex Chromosome Interchanges Produced By I-CreI Expression in DrosophilaPhotocross-linking of the homing endonuclease PI-SceI to its recognition sequence.Altered target site specificity variants of the I-PpoI His-Cys box homing endonuclease.Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae.A synthetic homing endonuclease-based gene drive system in the human malaria mosquitoComprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering.The nicking homing endonuclease I-BasI is encoded by a group I intron in the DNA polymerase gene of the Bacillus thuringiensis phage Bastille.Rules for DNA target-site recognition by a lactococcal group II intron enable retargeting of the intron to specific DNA sequences.Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytesDetermining the specificities of TALENs, Cas9, and other genome-editing enzymesDNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Targeted mutagenesis by homologous recombination in D. melanogaster.Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stabilityA new method for evaluating the specificity of indirect readout in protein-DNA recognition.Homing endonucleases catalyze double-stranded DNA breaks and somatic transgene excision in Aedes aegypti.Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preferenceHoming endonucleases: from microbial genetic invaders to reagents for targeted DNA modification.Genome modifications in plant cells by custom-made restriction enzymes.Generation and analysis of mesophilic variants of the thermostable archaeal I-DmoI homing endonuclease.R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+.Rapid evolution of the DNA-binding site in LAGLIDADG homing endonucleases.Degeneration of a homing endonuclease and its target sequence in a wild yeast strain.HLA-restricted presentation of WT1 tumor antigen in B-lymphoblastoid cell lines established using a maxi-EBV system.Double-strand breaks repair by gene conversion in silkworm holocentric chromosomes.Functional alpha-fragment of beta-galactosidase can be expressed from the mobile group I intron PpLSU3 embedded in yeast pre-ribosomal RNA derived from the chromosomal rDNA locusProduction of high-titer Epstein-Barr virus recombinants derived from Akata cells by using a bacterial artificial chromosome systemPushing the limits of what is achievable in protein-DNA docking: benchmarking HADDOCK's performance.
P2860
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P2860
I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@ast
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@en
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@nl
type
label
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@ast
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@en
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@nl
prefLabel
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@ast
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@en
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@nl
P2093
P3181
P356
P1476
I-PpoI and I-CreI homing site ...... sequential in vitro enrichment
@en
P2093
G M Argast
K M Stephens
R J Monnat
P304
P3181
P356
10.1006/JMBI.1998.1886
P407
P577
1998-07-17T00:00:00Z