DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier. - Wikidata - wikimedia - TriplyDB

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

http://www.wikidata.org/entity/Q35541255

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DNA Damage Response in Hematopoietic Stem Cell Ageing Hijacked in cancer: the KMT2 (MLL) family of methyltransferases Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic Cells Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia.MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia.ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion.Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1.The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors Epigenetics of hematopoiesis and hematological malignancies.Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cells EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling.Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function Efficacy of ATR inhibitors as single agents in Ewing sarcoma.Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors Genome instability of ageing stem cells--Induction and defence mechanisms Epigenetic modifiers in normal and malignant hematopoiesis.VII. Are lymphomas driven by epigenetic lesions?Mutation of cancer driver MLL2 results in transcription stress and genome instability.Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.Enhancer deregulation in cancer and other diseases.Distinct functions of histone H3, lysine 4 methyltransferases in normal and malignant hematopoiesis.NFkB is activated by multiple mechanisms in hairy cell leukemia.Modulation of urokinase plasminogen activator system by poly(ADP-ribose)polymerase-1 inhibition.SET/MLL family proteins in hematopoiesis and leukemia.Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.The DNA damage response pathway in normal hematopoiesis and malignancies.DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival.Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation.DNA damage tolerance in hematopoietic stem and progenitor cells in mice.Cancer, Oxidative Stress, and Metastasis.FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

http://www.wikidata.org/entity/Q35541255

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

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DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

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Amy Malhowski

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Andres Canela

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Aniruddha Deshpande

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Bioconductor: open software development for computational biology and bioinformatics

Gene ontology: tool for the unification of biology

Pathway Commons, a web resource for biological pathway data

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

TopHat: discovering splice junctions with RNA-Seq

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

Discovery and saturation analysis of cancer genes across 21 tumour types

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

DNA repair is limiting for haematopoietic stem cells during ageing

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