Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin
about
Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetasesAkt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 functionCharacterization of the interactions between mammalian PAZ PIWI domain proteins and DicerHeat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stabilityInhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicolHsp90 Inhibitors for the Treatment of Chronic Myeloid LeukemiaHSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative NeoplasmsGRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulumFragment screening using capillary electrophoresis (CEfrag) for hit identification of heat shock protein 90 ATPase inhibitorsIdentification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbitalInhibition of MDM2 by hsp90 contributes to mutant p53 stabilizationAssociation between Hsp90 and the ClC-2 chloride channel upregulates channel functionMitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injuryPosttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitorsGeldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperonesNatural iminosugar (+)-lentiginosine inhibits ATPase and chaperone activity of hsp90Genetic and genomic architecture of the evolution of resistance to antifungal drug combinationsThe membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cellsRegulation and function of the human HSP90AA1 geneChemistry and biology of resorcylic acid lactonesDivergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitorGenes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia.Expression-based Pathway Signature Analysis (EPSA): mining publicly available microarray data for insight into human disease.Single plasmids expressing human steroid hormone receptors and a reporter gene for use in yeast signaling assays.Geldanamycin Reduces Acute Respiratory Distress Syndrome and Promotes the Survival of Mice Infected with the Highly Virulent H5N1 Influenza Virus.Geldanamycin attenuates 3‑nitropropionic acid‑induced apoptosis and JNK activation through the expression of HSP 70 in striatal cells.Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationshipsHost cell factor requirement for hepatitis C virus enzyme maturationProtein chaperones: a composition of matter review (2008 - 2013).Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogsHeat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin.Picornavirus morphogenesis.Molecular chaperone Hsp90 is important for vaccinia virus growth in cellsLigand-induced conformational shift in the N-terminal domain of GRP94, an Hsp90 chaperone.Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise.Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells.A chemical genomic study identifying diversity in cell migration signaling in cancer cells.HSP90 as a new therapeutic target for cancer therapy: the story unfolds.Development of a Selective Medium for the Fungal Pathogen Cylindrocarpon destructans Using Radicicol
P2860
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P2860
Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Antibiotic radicicol binds to ...... c activities with geldanamycin
@ast
Antibiotic radicicol binds to ...... c activities with geldanamycin
@en
Antibiotic radicicol binds to ...... c activities with geldanamycin
@nl
type
label
Antibiotic radicicol binds to ...... c activities with geldanamycin
@ast
Antibiotic radicicol binds to ...... c activities with geldanamycin
@en
Antibiotic radicicol binds to ...... c activities with geldanamycin
@nl
prefLabel
Antibiotic radicicol binds to ...... c activities with geldanamycin
@ast
Antibiotic radicicol binds to ...... c activities with geldanamycin
@en
Antibiotic radicicol binds to ...... c activities with geldanamycin
@nl
P2093
P3181
P1476
Antibiotic radicicol binds to ...... c activities with geldanamycin
@en
P2093
B Stensgard
L M Neckers
T W Schulte
W Sullivan
P3181
P356
10.1379/1466-1268(1998)003<0100:ARBTTN>2.3.CO;2
P407
P577
1998-06-01T00:00:00Z