NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector - Wikidata - wikimedia - TriplyDB

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

http://www.wikidata.org/entity/Q28278566

about

The NQO1 Pro187Ser polymorphism and breast cancer susceptibility: evidence from an updated meta-analysis Cancer chemoprevention by citrus pulp and juices containing high amounts of β-cryptoxanthin and hesperidin Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase(1.)Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?Implications of NQO1 in cancer therapy Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier?Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition In Silico Screening Reveals Structurally Diverse, Nanomolar Inhibitors of NQO2 That Are Functionally Active in Cells and Can Modulate NF- B Signaling Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane Biphasic regulation of the NADPH oxidase by HGF/c-Met signaling pathway in primary mouse hepatocytes Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis Individual expression features of GPX2, NQO1 and SQSTM1 transcript variants induced by hydrogen peroxide treatment in HeLa cells.Oxidative status interactome map: towards novel approaches in experiment planning, data analysis, diagnostics and therapy.SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.Downregulation of NAD(P)H:quinone oxidoreductase 1 inhibits proliferation, cell cycle and migration of cholangiocarcinoma cells.Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells.Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti-drug responses in human non-small cell lung cancer Polo-like kinase 2 activates an antioxidant pathway to promote the survival of cells with mitochondrial dysfunction.The effects of idebenone on mitochondrial bioenergetics A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion.Dietary regulation of Keap1/Nrf2/ARE pathway: focus on plant-derived compounds and trace minerals.Cardioprotective role of P38 MAPK during myocardial infarction via parallel activation of α-crystallin B and Nrf2.A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population.A genetic basis for the variation in the vulnerability of cancer to DNA damage.Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway Stimulation of phagocytosis by sulforaphane.A rapid transcriptome response is associated with desiccation resistance in aerially-exposed killifish embryos.Genetic evidence for NAD(P)H:quinone oxidoreductase 1-catalyzed quinone reduction on passage through the mouse pulmonary circulation.

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NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

http://www.wikidata.org/entity/Q28278566

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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J.ABB.2010.03.019

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Archives of Biochemistry and Biophysics

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NAD(P)H:quinone acceptor oxido ...... onally versatile cytoprotector

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Albena T Dinkova-Kostova

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Paul Talalay

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P2860

A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity

NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b)

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release

NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

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10.1016/J.ABB.2010.03.019

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