Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor
about
Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.Crucial structural role for the PH and C1 domains of the Vav1 exchange factorRational design of small molecule inhibitors targeting RhoA subfamily Rho GTPasesThe DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationPhosphorylation-mediated regulation of GEFs for RhoARegulation of small GTPases by GEFs, GAPs, and GDIsCrystal structure of the rac activator, Asef, reveals its autoinhibitory mechanismA Catalytic Coiled Coil: Structural Insights into the Activation of the Rab GTPase Sec4p by Sec2pCrystal structure of the Sec4p{middle dot}Sec2p complex in the nucleotide exchanging intermediate stateStructure of Shigella IpgB2 in Complex with Human RhoA: IMPLICATIONS FOR THE MECHANISM OF BACTERIAL GUANINE NUCLEOTIDE EXCHANGE FACTOR MIMICRYActivated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for AutoregulationThe Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinInsights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.Structure of the Rho-specific guanine nucleotide-exchange factor XplnStructural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2Structural Insights into the Activation of the RhoA GTPase by the Lymphoid Blast Crisis (Lbc) OncoproteinYeast AEP3p is an accessory factor in initiation of mitochondrial translation.Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complexCharacterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1PAK1 negatively regulates the activity of the Rho exchange factor NET1Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complexAutoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker.Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteinsThe solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.Dissecting the thermodynamics of GAP-RhoA interactions.Toward understanding RhoGTPase specificity: structure, function and local activation.HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assayExploring functional roles of multibinding protein interfaces.Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.Finding consistent disease subnetworks across microarray datasets.Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEFUse of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasionA structural model reveals energy transduction in dynein.The Galpha12-RGS RhoGEF-RhoA signalling pathway regulates neurotransmitter release in C. elegans.Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
P2860
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P2860
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structural determinants of Rho ...... ine-nucleotide exchange factor
@ast
Structural determinants of Rho ...... ine-nucleotide exchange factor
@en
Structural determinants of Rho ...... ine-nucleotide exchange factor
@nl
type
label
Structural determinants of Rho ...... ine-nucleotide exchange factor
@ast
Structural determinants of Rho ...... ine-nucleotide exchange factor
@en
Structural determinants of Rho ...... ine-nucleotide exchange factor
@nl
prefLabel
Structural determinants of Rho ...... ine-nucleotide exchange factor
@ast
Structural determinants of Rho ...... ine-nucleotide exchange factor
@en
Structural determinants of Rho ...... ine-nucleotide exchange factor
@nl
P2093
P2860
P3181
P356
P1476
Structural determinants of Rho ...... ine-nucleotide exchange factor
@en
P2093
John J G Tesmer
Romana Kristelly
P2860
P304
P3181
P356
10.1074/JBC.M406056200
P407
P577
2004-11-05T00:00:00Z