cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III
about
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicalsRole of the tryptophan residue in the vicinity of the catalytic center of exonuclease III family AP endonucleases: AP site recognition mechanism.The current state of eukaryotic DNA base damage and repairBase excision repair and cancerThe molecular basis of asbestos induced lung injuryIncision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNADynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and productMechanism underlying replication protein a stimulation of DNA ligase I.Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigenTaking U out, with two nucleases?Small molecule inhibitors of DNA repair nuclease activities of APE1.Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.Posttranslational modification of mammalian AP endonuclease (APE1).Drosophila Rrp1 3'-exonuclease: demonstration of DNA sequence dependence and DNA strand specificity.Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.In situ activity gel for DNA repair 3'-phosphodiesterase.Regulation of eukaryotic abasic endonucleases and their role in genetic stabilityElements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases.The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domainsExploiting base excision repair to improve therapeutic approaches for pancreatic cancerDrosophila Rrp1 complements E. coli xth nfo mutants: protection against both oxidative and alkylation-induced DNA damage.WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups.An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP siteLife without DNA repairUse of PCR-enzyme immunoassay for identification of influenza A virus matrix RNA in clinical samples negative for cultivable virus.Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.Transient-state kinetics of apurinic/apyrimidinic (AP) endonuclease 1 acting on an authentic AP site and commonly used substrate analogs: the effect of diverse metal ions and base mismatches.Human apurinic/apyrimidinic endonuclease 1.Characterization of the promoter region of the human apurinic endonuclease gene (APE).Characterization of the AP endonucleases from Thermoplasma volcanium and Lactobacillus plantarum: Contributions of two important tryptophan residues to AP site recognition.Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding.The open reading frame 1 of the L1Tc retrotransposon of Trypanosoma cruzi codes for a protein with apurinic-apyrimidinic nuclease activity.The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis.Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity.DNA damages processed by base excision repair: biological consequences.Role of active site tyrosines in dynamic aspects of DNA binding by AP endonuclease.Key role of a downstream specificity protein 1 site in cell cycle-regulated transcription of the AP endonuclease gene APE1/APEX in NIH3T3 cells.The L1Tc, long interspersed nucleotide element from Trypanosoma cruzi, encodes a protein with 3'-phosphatase and 3'-phosphodiesterase enzymatic activities.AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair.New nucleotide sequence data on the EMBL File Server
P2860
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P2860
cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@ast
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@en
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@nl
type
label
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@ast
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@en
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@nl
prefLabel
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@ast
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@en
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@nl
P2093
P1476
cDNA cloning, sequencing, expr ...... cherichia coli exonuclease III
@en
P2093
P304
P356
10.1016/0167-4781(92)90027-W
P407
P577
1992-07-15T00:00:00Z