Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity
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Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesNeurotransmitter release: the last millisecond in the life of a synaptic vesicleDeconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypesComplexins: small but capableThe schizophrenia risk gene product miR-137 alters presynaptic plasticity.Ring-like oligomers of Synaptotagmins and related C2 domain proteinsAn extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.Differences in human cortical gene expression match the temporal properties of large-scale functional networks.Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library.Re-examining how complexin inhibits neurotransmitter release.Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivoComplexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanismsSynaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathyMembrane curvature sensing by the C-terminal domain of complexin.Calcium sensitive ring-like oligomers formed by synaptotagminCauses and consequences of crossing-over evidenced via a high-resolution recombinational landscape of the honey bee.The EHD protein Past1 controls postsynaptic membrane elaboration and synaptic function.Molecular underpinnings of synaptic vesicle pool heterogeneity.Transmission, Development, and Plasticity of Synapses.Phosphorylation of Complexin by PKA Regulates Activity-Dependent Spontaneous Neurotransmitter Release and Structural Synaptic Plasticity.Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complexInteraction of the complexin accessory helix with the C-terminus of the SNARE complex: molecular-dynamics model of the fusion clamp.N-terminal domain of complexin independently activates calcium-triggered fusion.Molecular mechanisms of COMPLEXIN fusion clamp function in synaptic exocytosis revealed in a new Drosophila mutantInsulin signaling controls neurotransmission via the 4eBP-dependent modification of the exocytotic machinery.Spontaneous and evoked release are independently regulated at individual active zonesConformational dynamics of calcium-triggered activation of fusion by synaptotagmin.Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells.C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice.Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous NeurotransmissionPreincubation of t-SNAREs with Complexin I Increases Content-Mixing Efficiency.Retrograde BMP signaling modulates rapid activity-dependent synaptic growth via presynaptic LIM kinase regulation of cofilin.Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics.Electrophysiological analysis of synaptic transmission in Drosophila.Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt-Jakob Disease.A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion.Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless.Is it zippered? Does it flare? That darn complexin clamping SNARE.Interaction of the Complexin Accessory Helix with Synaptobrevin Regulates Spontaneous Fusion.
P2860
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P2860
Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Complexin controls spontaneous ...... ties of synaptotagmin activity
@ast
Complexin controls spontaneous ...... ties of synaptotagmin activity
@en
Complexin controls spontaneous ...... ties of synaptotagmin activity
@nl
type
label
Complexin controls spontaneous ...... ties of synaptotagmin activity
@ast
Complexin controls spontaneous ...... ties of synaptotagmin activity
@en
Complexin controls spontaneous ...... ties of synaptotagmin activity
@nl
prefLabel
Complexin controls spontaneous ...... ties of synaptotagmin activity
@ast
Complexin controls spontaneous ...... ties of synaptotagmin activity
@en
Complexin controls spontaneous ...... ties of synaptotagmin activity
@nl
P2093
P2860
P3181
P1476
Complexin controls spontaneous ...... ties of synaptotagmin activity
@en
P2093
J Troy Littleton
Ramon A Jorquera
Richard W Cho
Sarah Huntwork-Rodriguez
Yulia Akbergenova
P2860
P304
P3181
P356
10.1523/JNEUROSCI.3212-12.2012
P407
P577
2012-12-12T00:00:00Z