Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
about
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory SmadsSmad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationIdentification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analysesJab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradationAxin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signalingInteraction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosisTransforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanismArkadia amplifies TGF-beta superfamily signalling through degradation of Smad7Smad7 induces hepatic metastasis in colorectal cancerRole of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisSmad6 as a transcriptional corepressorSmad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosisParticipation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulaThe TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancerChromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signalingDecreased Smad 7 expression contributes to cardiac fibrosis in the infarcted rat heartThe role of Smad signaling in hematopoiesis.An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer.Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in miceOVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis.The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.Bone morphogenetic proteins and their antagonists: current and emerging clinical uses.The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions.A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival.A novel library screen identifies immunosuppressors that promote osteoblast differentiation.FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle.Smad signalling in the ovaryPreferential utilization of Imp7/8 in nuclear import of SmadsTransforming growth factor Beta family: insight into the role of growth factors in regulation of fracture healing biology and potential clinical applications.Lung remodeling in a mouse model of asthma involves a balance between TGF-β1 and BMP-7Control of the nuclear localization of Extradenticle by competing nuclear import and export signals.Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation.The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart.Regulating the stability of TGFbeta receptors and Smads.The role of epithelial mesenchymal transition markers in thyroid carcinoma progression.
P2860
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P2860
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@ast
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@en
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@nl
type
label
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@ast
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@en
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@nl
prefLabel
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@ast
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@en
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@nl
P2093
P2860
P356
P1476
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
@en
P2093
P2860
P304
P356
10.1074/JBC.273.44.29195
P407
P577
1998-10-30T00:00:00Z