The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
about
Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAKWIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cellsPaxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayNIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domainTyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migrationRecruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationNck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activationIdentification of a new Pyk2 target protein with Arf-GAP activityWiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cellsRegulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteinsExpression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexesNck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathwaysPaxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin networkPolyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorptionDissecting Nck/Dock signaling pathways in Drosophila visual system.Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosisAkt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migrationThe Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1)Molecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsSRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migrationCell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotypeMaturin is a novel protein required for differentiation during primary neurogenesisMembrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cellsTemporal and spatial distribution of activated Pak1 in fibroblastsRho GTPases and their effector proteins3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.Autoinhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity.Nck adapter proteins: functional versatility in T cellsActivation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.The Ste20 kinase misshapen regulates both photoreceptor axon targeting and dorsal closure, acting downstream of distinct signalsA role for p21-activated kinase in endothelial cell migration.Angiotensin II stimulates serine phosphorylation of the adaptor protein Nck: physical association with the serine/threonine kinases Pak1 and casein kinase IRole of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques
P2860
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P2860
The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@ast
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@en
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@nl
type
label
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@ast
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@en
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@nl
prefLabel
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@ast
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@en
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@nl
P2093
P1476
The adaptor protein Nck links ...... e serine-threonine kinase Pak1
@en
P2093
E Y Skolnik
J Chernoff
J Schlessinger
M L Galisteo
P304
20997-1000
P407
P577
1996-08-30T00:00:00Z