Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation - Wikidata - wikimedia - TriplyDB

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

http://www.wikidata.org/entity/Q28290595

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Structural characterization of human cytochrome P450 2C19: active site differences between P450s 2C8, 2C9, and 2C19 Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A CYP2B6 and bupropion's smoking-cessation pharmacology: the role of hydroxybupropion Safety issues of current analgesics: an update Pharmacogenetics as a tool to tailor antiretroviral therapy: A review Marine invertebrate xenobiotic-activated nuclear receptors: their application as sensor elements in high-throughput bioassays for marine bioactive compounds Structural diversity of eukaryotic membrane cytochrome p450s Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound Precision medicine: from pharmacogenomics to pharmacoproteomics Drug Metabolism - From In Vitro to In Vivo, From Simple to Complex: Reflections of the BCPT Nordic Prize 2014 Awardee Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6 Gene expression variability in human hepatic drug metabolizing enzymes and transporters CYB5D2 requires heme-binding to regulate HeLa cell growth and confer survival from chemotherapeutic agents Effect of Cytochrome b5 Content on the Activity of Polymorphic CYP1A2, 2B6, and 2E1 in Human Liver Microsomes Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation.Drug Interaction Potential of Osilodrostat (LCI699) Based on Its Effect on the Pharmacokinetics of Probe Drugs of Cytochrome P450 Enzymes in Healthy Adults No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma.The Impact of CYP2D6 Genotyping on Tamoxifen Treatment Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17 Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patients with type 2 diabetes mellitus Basic review of the cytochrome p450 system.CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response.Liver-specific cytochrome P450 CYP2C22 is a direct target of retinoic acid and a retinoic acid-metabolizing enzyme in rat liver.Implementing genotype-guided antithrombotic therapy.Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Statins and breast cancer prognosis: evidence and opportunities.Influence of environmental and genetic factors on CYP1A2 activity in individuals of South Asian and European ancestry.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Understanding and preventing drug-drug and drug-gene interactions.Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.Pharmacogenomics of antimicrobial agents.Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells.Pharmacogenetics in Ghana: reviewing the evidence.SNP genotyping using TaqMan technology: the CYP2D6*17 assay conundrum.Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.Human hepatic cytochrome P450-specific metabolism of the organophosphorus pesticides methyl parathion and diazinon.Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX

P2860

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P2860

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

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2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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Analytical and Bioanalytical Chemistry

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Functional pharmacogenetics/ge ...... lved in drug biotransformation

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Kathrin Klein

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Matthias Schwab

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P2860

Unraveling gene-gene interactions regulated by ligands of the aryl hydrocarbon receptor.

Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.

The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

Short communication: high prevalence of the cytochrome P450 2C8*2 mutation in Northern Ghana.

[[Inflammation and drug metabolism: NF-kappB and the CAR and PXR xeno-receptors].

Sex is a major determinant of CYP3A4 expression in human liver

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s00216-008-2291-6

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1093-1108

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scholarly article

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3338468

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10.1007/S00216-008-2291-6

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6

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392

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Ulrich M. Zanger

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2008-08-10T00:00:00Z

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18695978

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