Sex is a major determinant of CYP3A4 expression in human liver
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Genetic predictors of interindividual variability in hepatic CYP3A4 expressionMuscular effects of statins in the elderly female: a reviewFunctionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping testsFunctional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformationMetabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolismTranscriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery diseasePerinatal exposure to perfluorooctane sulfonate affects glucose metabolism in adult offspringQualitative de novo analysis of full length cDNA and quantitative analysis of gene expression for common marmoset (Callithrix jacchus) transcriptomes using parallel long-read technology and short-read sequencingRole of TRPA1 in Acute Cardiopulmonary Toxicity of Inhaled AcroleinPrediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling.Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation.Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3Statins are related to impaired exercise capacity in males but not females.Human liver expression of CYP2C8: gender, age, and genotype effects.A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.Evaluation of sexual dimorphism in the efficacy and safety of simvastatin/atorvastatin therapy in a southern Brazilian cohort.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents.Update information on drug metabolism systems--2009, part II: summary of information on the effects of diseases and environmental factors on human cytochrome P450 (CYP) enzymes and transporters.Unbiased, genome-wide in vivo mapping of transcriptional regulatory elements reveals sex differences in chromatin structure associated with sex-specific liver gene expressionCytochrome P450 and xenobiotic receptor humanized mice.Sex differences in drug disposition.CYP3A4 and pregnane X receptor humanized mice.Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients.Pharmacogenetics of anxiolytic drugs.Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosisPathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.Sex differences in the effectiveness of statins after myocardial infarction.Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugsGender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapyLack of sex-related differences in saquinavir pharmacokinetics in an HIV-seronegative cohort.Effect of widely used combinations of antiretroviral therapy on liver CYP3A4 activity in HIV-infected patients.Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common EventSex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood.Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ miceDifferential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms
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P2860
Sex is a major determinant of CYP3A4 expression in human liver
description
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
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wetenschappelijk artikel
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наукова стаття, опублікована в жовтні 2003
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name
Sex is a major determinant of CYP3A4 expression in human liver
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Sex is a major determinant of CYP3A4 expression in human liver
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type
label
Sex is a major determinant of CYP3A4 expression in human liver
@en
Sex is a major determinant of CYP3A4 expression in human liver
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prefLabel
Sex is a major determinant of CYP3A4 expression in human liver
@en
Sex is a major determinant of CYP3A4 expression in human liver
@nl
P356
P1433
P1476
Sex is a major determinant of CYP3A4 expression in human liver
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P2093
P304
P356
10.1053/JHEP.2003.50393
P407
P577
2003-10-01T00:00:00Z