The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
about
Tyrosine hydroxylase and regulation of dopamine synthesisParkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residuesThe role of oxidative stress in Parkinson's diseaseOxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1Mitochondrial localization of DJ-1 leads to enhanced neuroprotectionProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesHuman Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersStructural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1 † , ‡Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1Genetics in Parkinson disease: Mendelian versus non-Mendelian inheritanceCross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for CancerDJ-1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-MycDJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidaseDJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE)Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injuryStructural effects of Parkinson's disease linked DJ-1 mutations.DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex.Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stressBiophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe.BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia.DJ-1, PINK1, and their effects on mitochondrial pathwaysDJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.Protein aggregation in a mutant deficient in yajL, the bacterial homolog of the Parkinsonism-associated protein DJ-1Immunostaining of oxidized DJ-1 in human and mouse brainsNeuroproteomics as a promising tool in Parkinson's disease research.The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's diseaseA plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasisTranslational defects in a mutant deficient in YajL, the bacterial homolog of the parkinsonism-associated protein DJ-1.Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.The genetics of Parkinson disease.
P2860
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P2860
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@ast
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@en
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@nl
type
label
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@ast
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@en
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@nl
prefLabel
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@ast
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@en
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@nl
P2093
P3181
P1476
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
@en
P2093
Anthony L Fink
Mark A Wilson
Wenbo Zhou
P304
P3181
P356
10.1016/J.JMB.2005.12.030
P407
P577
2006-03-03T00:00:00Z