DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70. - Wikidata - wikimedia - TriplyDB

DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.

DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.

http://www.wikidata.org/entity/Q33326619

about

Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection Hydrogel-based nanocomposites and mesenchymal stem cells: a promising synergistic strategy for neurodegenerative disorders therapy Crystal Structure of Filamentous Aggregates of Human DJ-1 Formed in an Inorganic Phosphate-dependent Manner Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling The Pseudomonas aeruginosa pfpI gene plays an antimutator role and provides general stress protection BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.The genetics of Parkinson disease.The role of cysteine oxidation in DJ-1 function and dysfunction.Neuroprotective effects of protocatechuic aldehyde against neurotoxin-induced cellular and animal models of Parkinson's disease.DJ-1 can inhibit microtubule associated protein 1 B formed aggregates DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.Molecular chaperones in Parkinson's disease--present and future A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake Mitochondrial dysfunction in genetic animal models of Parkinson's disease Role of renal DJ-1 in the pathogenesis of hypertension associated with increased reactive oxygen species production Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process Hsp31, a member of the DJ-1 superfamily, is a multitasking stress responder with chaperone activity.Genetic insights into sporadic Parkinson's disease pathogenesis.Mitochondrial quality control and neurological disease: an emerging connection.Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis.Peripheral biomarkers of Parkinson's disease as early reporters of central neurodegeneration.Protective role of heat shock proteins in Parkinson's disease.Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease.Mitochondrial contribution to Parkinson's disease pathogenesis.Aberrant protein s-nitrosylation in neurodegenerative diseases.Loss of functional alpha-synuclein: a toxic event in Parkinson's disease?The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents.Loss of Mitochondrial Function Impairs Lysosomes.Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy.Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism.Chaperone-Based Therapies for Disease Modification in Parkinson's Disease.The Aggregation of Huntingtin and α-Synuclein.

P2860

Q26781796-6D6376FC-4A29-45ED-8871-BBBC2E1DFF2D Q27027614-10E85C88-1B87-4A01-AAF3-725564BC6FA7 Q27652523-0E0E0142-1423-4D43-8EA0-52573FB438C5 Q27934988-5FC72965-D7D4-41D5-917F-1B0CA353C08E Q28475159-BB308D94-DE0D-43E2-87DF-FA6BF3B01D19 Q33386642-A7A4C671-6C5D-4F9E-B99E-F147342A343E Q33689625-9B896F92-DF67-4B11-A4E1-FB7E4840DC4A Q33755817-1F56A2D9-2E1E-423B-85A3-D157296BAD99 Q34014666-FB1B4A24-03D1-4778-A09C-462C23253683 Q34078603-33F0B15F-6576-423F-9F68-D7C1DD7DCB75 Q34604083-AD5BB943-7EEC-4B03-8599-A9BC38F687BB Q35031181-8E74B474-0FFC-4C87-9C9E-814CD27507EE Q35036220-6E6D42F4-E2F5-4070-8916-3E8E1DA01717 Q35061270-F1006944-756B-43B7-8641-0513DF3F6DC7 Q35269486-2C93D170-EAB5-492B-AE29-22138C0FC5C0 Q35688796-9B7E0FE3-C29D-4100-947A-B1749BF92F90 Q35754644-357DFFA4-9FE9-4128-9D12-3D458931DED1 Q35799109-7BEA243C-F676-45C8-9A9E-61488EED5EC4 Q36090196-80528279-63A1-44ED-AB78-3E2FB6B62F95 Q36139835-0C51A3EF-5D85-4F22-8A98-6B9A8981F81E Q37167865-DACC8A57-0786-49CF-AD66-0AAB2DE29860 Q37583402-B53BBC31-47B9-43E5-A293-6ADDE79F0D84 Q37732485-464CB922-D5B4-40C1-9EAD-211B4605937E Q37739259-51ED7CF6-DBCA-483E-AA05-081E5BEA0577 Q37755118-01DD07C7-345A-4191-8178-E7EF44CF8E92 Q37826616-A72461F9-2BBC-4B34-8268-E600C03E44BB Q37889815-2C02BCAC-E32D-46BF-819C-1AA68B713717 Q37891820-CD414DCD-81B3-4B86-A528-2FB2CCE7BDDB Q38110376-DE53D799-D30B-4FC0-A438-B5605F6F32E3 Q38128456-0C395EC3-00A3-4480-9D5F-625C5CBE1700 Q38202314-43FB3C9B-33D2-406B-96D7-EC2398A19DF8 Q38775811-C3593E9D-C380-4DE3-BF8E-0B65122EE5FB Q38785393-5A393CC4-C114-414A-84E0-02B7FE27A5E4 Q39062259-589849C4-9504-4F34-877E-7FFB84D61D00 Q39225981-2BCBAF59-4F2D-435F-9F47-59897E4B4EA2 Q40987726-2D5D883D-2977-400F-AAEA-68BE99B46B09 Q41078288-33CB7FD6-782A-4764-85AE-FDF5D01FCC9A Q41448283-74A14E8F-D28A-45A2-BA9D-75E4B1AEDBCF Q41623081-41F64F0B-CEC3-4070-A5B1-244844C7C5D0 Q41834257-2C537992-A801-4CFF-81ED-B3C8ABA2805B

P2860

DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.

http://www.wikidata.org/entity/Q33326619

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@ast

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@en

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@nl

type

label

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@ast

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@en

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@nl

prefLabel

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@ast

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@en

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@nl

P1433

Q33326619-6C106B8B-EAEF-42B9-A713-76C30451A70C

P1476

Q33326619-4C60B696-4D6E-4862-ADC2-BEED0D6B6631

P2093

Q33326619-616584C2-905D-4D33-84A2-3408F78213DF

Q33326619-8788C63D-DD4A-4834-9891-968A948E89CC

Q33326619-8B4F7CCB-C8D1-49A4-9B30-5812757A67B3

Q33326619-A6984EB8-DF4C-43D3-A80E-B6B8FBC16BFA

Q33326619-AB01488D-528B-47C8-AE58-2A2365556BF7

P2860

Q33326619-04D64442-EFB1-4242-9334-ADA60FAB4CD7

Q33326619-1922A665-5DFA-4FB2-AC07-ED10DA5930B5

Q33326619-1F5DF637-C35C-4AEE-A8C9-FC62307D5652

Q33326619-29E58AB4-F9E9-4967-9E23-42CB4CBEA20F

Q33326619-330DF806-8FCF-46C8-AF21-31387D9752FE

Q33326619-3717F382-2D49-4F4B-9FF8-7A8763132A3B

Q33326619-3A9CC28C-70AE-46D8-8449-4C90E83F035C

Q33326619-3AB5E64B-EDBC-4B2C-A159-3D4CA38DD1AE

Q33326619-3BDD17AC-BADE-4FF1-B91B-8E9963B797BA

Q33326619-3E9850C8-67DA-4E07-9364-D164E37ABA0B

P304

Q33326619-0061DB5C-0ADA-42ED-BF93-94A7CCB55D97

P31

Q33326619-759BABCF-1BCC-41F6-B420-8BF9A43D015B

P356

Q33326619-10E4AAAE-28B1-4AF6-9C06-A0B9319B646F

P407

Q33326619-B7769542-AC86-4ECF-8566-4364899A236B

P433

Q33326619-43197513-08A1-47C3-8C6C-58A2700F1743

P478

Q33326619-F944E573-6678-4D12-A4F1-E7E0D3C92FA2

P50

Q33326619-13560686-F615-4E1D-91E3-F1318DC48399

Q33326619-7C65B77A-219D-475A-A062-083BE8615C24

Q33326619-A6D8F80E-807E-4A14-93E1-14191D3F9D8E

P577

Q33326619-EAAB19A5-8261-4AA0-B7A2-EF0B755700D4

P5875

Q33326619-F751CB52-238B-4670-8AF5-D0575EB368F4

P698

Q33326619-1FD3718F-3017-4F7F-9256-D0A031395818

P921

Q33326619-07DB357A-CAA3-4372-89B4-871E324F8806

Q33326619-856CFD7D-6F98-40C5-BB24-551ADF88A3AC

P932

Q33326619-00A4BEEF-D354-452F-A79C-3164753AA089

P356

JOURNAL.PONE.0001884

P1433

P1476

DJ-1 modulates alpha-synuclein ...... ease and involvement of HSP70.

@en

P2093

Alessandro Negro

http://www.w3.org/2001/XMLSchema#string

Francesca Prato

http://www.w3.org/2001/XMLSchema#string

Gianluigi Forloni

http://www.w3.org/2001/XMLSchema#string

Marzia Pesaresi

http://www.w3.org/2001/XMLSchema#string

Sara Batelli

http://www.w3.org/2001/XMLSchema#string

P2860

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease

DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

alpha-Synuclein locus triplication causes Parkinson's disease

Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease

The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

P304

e1884

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0001884

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

3

http://www.w3.org/2001/XMLSchema#string

P50

Raffaela Rametta

P577

2008-04-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5469367

http://www.w3.org/2001/XMLSchema#string

P698

18382667

http://www.w3.org/2001/XMLSchema#string

P921

Parkinson's disease

P932

2270347

http://www.w3.org/2001/XMLSchema#string