Natural and enantiomeric etiocholanolone interact with distinct sites on the rat alpha1beta2gamma2L GABAA receptor
about
Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function.Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptorsCharacteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes.Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetateNeurosteroids, stress and depression: potential therapeutic opportunities.Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2L GABA(A) receptor.Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort.Steroid interaction with a single potentiating site is sufficient to modulate GABA-A receptor function.Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.ent-Steroids: novel tools for studies of signaling pathways.Concise Synthesis of the Unnatural Sphingosine and Psychosine Enantiomer.Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation.The influence of the membrane on neurosteroid actions at GABA(A) receptors.Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.The sticky issue of neurosteroids and GABA(A) receptors.The use of symmetry in enantioselective synthesis: four pairs of chrysene enantiomers prepared from 19-nortestosterone.Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA-A receptor potentiation.
P2860
Q33836921-4960253A-6A59-49DA-90EE-A7EBF28A7951Q33861962-8664ECA6-9828-4E34-BD8D-E315FCFBBCF9Q34682219-7D6672B2-4A5B-49AC-BCF3-6031185A7EF3Q35629077-E9D40374-CB3B-40F5-A537-257910348AEFQ35748598-44418047-04D5-4F33-9CB5-1F04EF3EA702Q36147323-C8896452-F141-4911-B56C-3D47A1694CD9Q36456866-514BFAE3-7BD6-4A8D-8DC5-B4E9A0D2FCACQ36666746-FD067F27-C990-4A76-B7D5-E158A3C616A8Q36733478-01772636-DEFB-494C-A1F7-AEC646F80FAAQ36977473-DBF02DB3-1222-48C5-9974-42EAAE489B40Q37008508-A1F29557-103B-47DA-AB06-BAA32427C1A1Q37199165-5ACB7328-B143-47D1-AC7E-AB6D8538EAC2Q37240859-308BD1D1-4D22-4C32-A007-4BA22AC2CF32Q37356591-D2580CA8-49A6-41E5-A55C-E378237EB2C3Q37412456-D8624956-A769-4E95-B68E-094ABCFB4C91Q37434457-6AF04120-848D-4914-BCF1-6B393CAD08E2Q37525549-DA8E6FF1-11FD-489F-B241-D9FBACD4584FQ38259021-F572A812-AAED-408D-B2B6-C0015FB973B5Q39872152-521B407D-750B-483D-A37E-0813A14674C3Q39880689-16362D2A-F471-46EF-ACD8-52EBF355A283Q42020909-570AE237-5B4F-4A41-A74A-AA36FBD8628AQ48568862-FDFAD4C2-DD7C-418D-B5D8-1A3F0346E078
P2860
Natural and enantiomeric etiocholanolone interact with distinct sites on the rat alpha1beta2gamma2L GABAA receptor
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@ast
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@en
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@nl
type
label
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@ast
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@en
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@nl
prefLabel
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@ast
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@en
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@nl
P2093
P3181
P356
P1476
Natural and enantiomeric etioc ...... ha1beta2gamma2L GABAA receptor
@en
P2093
Bryson W Katona
Douglas F Covey
Gustav Akk
Joe Henry Steinbach
John Bracamontes
P304
P3181
P356
10.1124/MOL.106.033407
P407
P577
2007-06-01T00:00:00Z