Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer
about
Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathwayIdentification of a shared genetic susceptibility locus for coronary heart disease and periodontitisGenetic factors affecting patient responses to pancreatic cancer treatmentChemical genetic screening for compounds that preferentially inhibit growth of methylthioadenosine phosphorylase (MTAP)-deficient Saccharomyces cerevisiaeTranscriptional dissection of pancreatic tumors engrafted in mice.Germline Mutations in Mtap Cooperate with Myc to Accelerate Tumorigenesis in MiceExpression of MTAP inhibits tumor-related phenotypes in HT1080 cells via a mechanism unrelated to its enzymatic function.Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signalingPreclinical anticancer activity of DNA-based cleavage molecules.Comprehensive analysis of CDKN2A (p16INK4A/p14ARF) and CDKN2B genes in 53 melanoma index cases considered to be at heightened risk of melanomaATP13A3 and caveolin-1 as potential biomarkers for difluoromethylornithine-based therapies in pancreatic cancersMice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma.Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategiesIncreasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells.Downregulation of methylthioadenosin phosphorylase by homozygous deletion in gastric carcinoma.Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions.Downregulation of ornithine decarboxylase by pcDNA-ODCr inhibits gastric cancer cell growth in vitro.A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers.Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts.Commonly dysregulated genes in murine APL cells.An overview of polyamine metabolism in pancreatic ductal adenocarcinoma.Ornithine decarboxylase (ODC) expression pattern in human prostate tissues and ODC transgenic mice.Methylthioadenosine phosphorylase inactivation depends on gene deletion in laryngeal squamous cell carcinoma.
P2860
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P2860
Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@ast
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@en
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@nl
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label
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@ast
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@en
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@nl
prefLabel
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@ast
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@en
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@nl
P2093
P3181
P1476
Loss of methylthioadenosine ph ...... is common in pancreatic cancer
@en
P2093
Ahmad L Subhi
Baiqing Tang
Binaifer R Balsara
Deborah A Altomare
Harry S Cooper
John P Hoffman
Joseph R Testa
Neal J Meropol
Warren D Kruger
P304
P3181
P356
10.1158/1078-0432.CCR-04-0972
P407
P577
2004-11-01T00:00:00Z