CCN2 is required for bleomycin-induced skin fibrosis in mice
about
CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesisFibroblasts in fibrosis: novel roles and mediatorsRoles for CCN2 in normal physiological processesTaking aim at the extracellular matrix: CCN proteins as emerging therapeutic targetsNADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agentsAnti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosisCellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Mechanical tension increases CCN2/CTGF expression and proliferation in gingival fibroblasts via a TGFβ-dependent mechanism.CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling networkGingival fibroblasts display reduced adhesion and spreading on extracellular matrix: a possible basis for scarless tissue repair?Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma.Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.Identification of therapeutic covariant microRNA clusters in hypoxia-treated cardiac progenitor cell exosomes using systems biology.Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient miceGenetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling.Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repairCCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators.Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts.Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.CCN2 is required for recruitment of Sox2-expressing cells during cutaneous tissue repair.LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.Targeting pericyte differentiation as a strategy to modulate kidney fibrosis in diabetic nephropathy.A physiological role for connective tissue growth factor in early wound healingUnderstanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities.Conditional knockout of CTGF affects corneal wound healing.Possible strategies for anti-fibrotic drug intervention in scleroderma.Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissuesCCN2: a novel, specific and valid target for anti-fibrotic drug intervention.Cellular and molecular actions of CCN2/CTGF and its role under physiological and pathological conditions.Mesenchymal cells emerge as primary contributors to fibrosis in multiple tissues.Molecular mechanisms of atrial fibrosis: implications for the clinic.Blockade of PDGF Receptors by Crenolanib Has Therapeutic Effect in Patient Fibroblasts and in Preclinical Models of Systemic Sclerosis.SMAD3 and SP1/SP3 Transcription Factors Collaborate to Regulate Connective Tissue Growth Factor Gene Expression in Myoblasts in Response to Transforming Growth Factor β.CCN2 in Skin Fibrosis.Eureka! Ets a target for fibrosis!Fibroblast-Extracellular Matrix Interactions in Tissue FibrosisAutophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.Getting out of a sticky situation: targeting the myofibroblast in sclerodermaCCN2 modulates hair follicle cycling in mice.Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex.
P2860
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P2860
CCN2 is required for bleomycin-induced skin fibrosis in mice
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
CCN2 is required for bleomycin-induced skin fibrosis in mice
@ast
CCN2 is required for bleomycin-induced skin fibrosis in mice
@en
CCN2 is required for bleomycin-induced skin fibrosis in mice
@nl
type
label
CCN2 is required for bleomycin-induced skin fibrosis in mice
@ast
CCN2 is required for bleomycin-induced skin fibrosis in mice
@en
CCN2 is required for bleomycin-induced skin fibrosis in mice
@nl
prefLabel
CCN2 is required for bleomycin-induced skin fibrosis in mice
@ast
CCN2 is required for bleomycin-induced skin fibrosis in mice
@en
CCN2 is required for bleomycin-induced skin fibrosis in mice
@nl
P2093
P356
P1476
CCN2 is required for bleomycin-induced skin fibrosis in mice
@en
P2093
Andrew Leask
David J Abraham
Shangxi Liu
Xu Shi-wen
P304
P356
10.1002/ART.30074
P407
P577
2011-01-01T00:00:00Z