Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. - Wikidata - wikimedia - TriplyDB

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

http://www.wikidata.org/entity/Q36459320

about

The Roles of NDR Protein Kinases in Hippo Signalling YAP determines the cell fate of injured mouse hepatocytes in vivo.The Hippo signaling pathway provides novel anti-cancer drug targets.Recent advances in understanding contextual TGFβ signaling Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.Crosstalk between Hippo signalling and miRNAs in tumour progression.Targeting the Hippo signalling pathway for cancer treatment.Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway.MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation.Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.Suppression of miR-16 promotes tumor growth and metastasis through reversely regulating YAP1 in human cholangiocarcinoma.Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.Angiomotin-like 2 interacts with and negatively regulates AKT.Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer.YAP regulates liver size and function.The history and regulatory mechanism of the Hippo pathway.Hippo cascade controls lineage commitment of liver tumors in mice and humans.Evaluation of YAP signaling in a rat tympanic membrane under a continuous negative pressure load and in human middle ear cholesteatoma.Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.Targeting the Hippo Pathway Is a New Potential Therapeutic Modality for Malignant Mesothelioma.Alternative Splicing in the Hippo Pathway-Implications for Disease and Potential Therapeutic Targets.YAP/TAZ Activation as a Target for Treating Metastatic Cancer.The Hippo-YAP Pathway Regulates 3D Organ Formation and Homeostasis.Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET.SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells.Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expression

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P2860

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

http://www.wikidata.org/entity/Q36459320

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

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2015年學術文章

@zh

2015年學術文章

@zh-hant

name

Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

@ast

Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

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type

label

Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

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Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

@en

prefLabel

Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

@ast

Dysregulated YAP1/TAZ and TGF- ...... is in Mob1a/1b-deficient mice.

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PNAS.1517188113

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Proceedings of the National Academy of Sciences of the United States of America

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Dysregulated YAP1/TAZ and TGF- ...... sis in Mob1a/1b-deficient mice

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Akira Suzuki

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Andrew Leask

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Hiroki Goto

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Hiroki Hikasa

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Hiroki Kurihara

http://www.w3.org/2001/XMLSchema#string

Hiroshi Nishina

http://www.w3.org/2001/XMLSchema#string

Jia Wang

http://www.w3.org/2001/XMLSchema#string

Kazuwa Nakao

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Keishi Sugimachi

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Koshi Mimori

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P2860

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Yap1 acts downstream of α-catenin to control epidermal proliferation

Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

TEAD mediates YAP-dependent gene induction and growth control

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Crystal structure of a human Mob1 protein: toward understanding Mob-regulated cell cycle pathways

CCN2 is required for bleomycin-induced skin fibrosis in mice

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1

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113

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Takehiko Sasaki

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2015-12-22T00:00:00Z

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288001625

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26699479

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4711826

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