Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
about
Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassemblyDown-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cellsSlug regulates integrin expression and cell proliferation in human epidermal keratinocytesRho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunitiesInsidious changes in stromal matrix fuel cancer progressionRegulation of ROCK activity in cancerRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?A computational tool for quantitative analysis of vascular networksAP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins.Perspective: Flicking with flow: Can microfluidics revolutionize the cancer research?Collagen reorganization at the tumor-stromal interface facilitates local invasion.RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells.Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Rho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition.Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments.Mechanics, malignancy, and metastasis: the force journey of a tumor cellIntegrins in development and cancer.Treatment with a rho kinase inhibitor improves survival from graft-versus-host disease in mice after MHC-haploidentical hematopoietic cell transplantation.Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.17β-Estradiol enhances breast cancer cell motility and invasion via extra-nuclear activation of actin-binding protein ezrin.Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasionRhoC, vascular endothelial growth factor and microvascular density in esophageal squamous cell carcinoma.Perturbation of cytoskeleton dynamics by the opposing effects of Rac1 and Rac1b.ROCK inhibition activates MCF-7 cellsTumor mechanics and metabolic dysfunction.Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells.RhoC and ROCKs regulate cancer cell interactions with endothelial cells.Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients.Immunohistochemical evaluation of ROCK activation in invasive breast cancerMechanobiology of tumor invasion: engineering meets oncology.Microenvironmental control of the breast cancer cell cycle.Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial TissuesTumor-induced remote ECM network orientation steers angiogenesis.A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II.Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility.The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment.Actin-myosin-based contraction is responsible for apoptotic nuclear disintegrationA tense situation: forcing tumour progression.Mechanical homeostasis is altered in uterine leiomyoma.Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses.
P2860
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P2860
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@ast
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@en
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@nl
type
label
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@ast
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@en
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@nl
prefLabel
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@ast
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@en
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@nl
P2093
P3181
P1433
P1476
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
@en
P2093
Christopher J Marshall
Daniel R Croft
Georgia Mavria
Shuixing Li
William M F Lee
P304
P3181
P356
10.1158/0008-5472.CAN-04-2052
P407
P577
2004-12-15T00:00:00Z