Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin - Wikidata - wikimedia - TriplyDB

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

http://www.wikidata.org/entity/Q28300614

about

Identification of direct protein targets of small molecules Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis Vanadate induction of NF-kB involves IkB kinase B and SAPK/ERK kinasa 1 in macrophages Proteasomal interference prevents zona pellucida penetration and fertilization in mammals Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells Subunit arrangement in the human 20S proteasome Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations.Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability PA200, a nuclear proteasome activator involved in DNA repair.Subcellular recruitment of fibrillarin to nucleoplasmic proteasomes: implications for processing of a nucleolar autoantigen.A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2 Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2 Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation Intrinsic evolutionary constraints on protease structure, enzyme acylation, and the identity of the catalytic triad Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein Structural Analysis of Spiro β-Lactone Proteasome Inhibitors Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition Omuralide and vibralactone: differences in the proteasome- β-lactone-γ-lactam binding scaffold alter target preferences A Minimal β-Lactone Fragment for Selective β5c or β5i Proteasome Inhibitors Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation.The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing.Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

P2860

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P2860

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

http://www.wikidata.org/entity/Q28300614

description

1995 nî lūn-bûn

@nan

1995 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի մայիսին հրատարակված գիտական հոդված

@hy

1995年の論文

@ja

1995年論文

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1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

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1995年论文

@wuu

name

Inhibition of proteasome activ ...... ne modification by lactacystin

@ast

Inhibition of proteasome activ ...... ne modification by lactacystin

@en

Inhibition of proteasome activ ...... ne modification by lactacystin

@nl

type

label

Inhibition of proteasome activ ...... ne modification by lactacystin

@ast

Inhibition of proteasome activ ...... ne modification by lactacystin

@en

Inhibition of proteasome activ ...... ne modification by lactacystin

@nl

prefLabel

Inhibition of proteasome activ ...... ne modification by lactacystin

@ast

Inhibition of proteasome activ ...... ne modification by lactacystin

@en

Inhibition of proteasome activ ...... ne modification by lactacystin

@nl

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SCIENCE.7732382

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Inhibition of proteasome activ ...... ne modification by lactacystin

@en

P2093

E J Corey

http://www.w3.org/2001/XMLSchema#string

S Choi

http://www.w3.org/2001/XMLSchema#string

S L Schreiber

http://www.w3.org/2001/XMLSchema#string

W S Lane

http://www.w3.org/2001/XMLSchema#string

P2860

cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

Cyclin is degraded by the ubiquitin pathway

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Homology of proteasome subunits to a major histocompatibility complex-linked LMP gene

Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome)

Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins

The ubiquitin system for protein degradation

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

The ubiquitin-proteasome proteolytic pathway

P304

726-731

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scholarly article

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4070369

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10.1126/SCIENCE.7732382

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5211

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268

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Robert F. Standaert

Gabriel Fenteany

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1995-05-01T00:00:00Z

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15467571

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7732382

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