Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
about
The A20-binding protein ABIN-2 exerts unexpected function in mediating transcriptional coactivationA mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradationLKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivoLoss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneityThe Gordon Wilson Lecture: The clinical legacy of Jonathan Hutchinson (1828-1913): syndromology and dysmorphology meet genomicsProtean PTEN: form and functionFyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1Hamartomatous polyposis syndromesGermline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancersSTK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreasColorectal cancer risk in hamartomatous polyposis syndromesLKB1 associates with Brg1 and is necessary for Brg1-induced growth arrestLKB1 as the ghostwriter of crypt historyLKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testisGenetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage ConsortiumNovel DNA copy number losses in chromosome 12q12--q13 in adenoid cystic carcinomaDifferent pattern of loss of heterozygosity among endocervical-type adenocarcinoma, endometrioid-type adenocarcinoma and adenoma malignum of the uterine cervix.A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Indian patients.Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestineMutations in STK11 gene in Czech Peutz-Jeghers patientsDistinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci.LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis.Peutz-Jeghers syndromePeutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.DNA copy number losses in human neoplasms.High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.Hereditary hamartomatous polyposis syndromes: understanding the disease risks as children reach adulthood.Methods of molecular analysis: assessing losses and gains in tumoursInherited predisposition to pancreatic cancer.Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistanceRole of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposisChromosome imbalances in familial gliomas detected by comparative genomic hybridization.Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.Review article: the prevention of colorectal cancer.Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.Clinical genetics of multiple endocrine neoplasias, Carney complex and related syndromes.Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangiomyomatosis.A gene for familial juvenile polyposis maps to chromosome 18q21.1.Germline mutations of the LKB1 (STK11) gene in Peutz-Jeghers patients.
P2860
Q24302016-E068AEA6-A495-435E-808E-3799B0FB27CEQ24306061-A3E7EE82-C804-48D7-8567-5D3CB618B42EQ24531930-0690B53B-EA00-4D7E-962D-E34550F994C7Q24539769-ABD77EA7-A3B0-4946-808C-48D788938AF6Q24546246-07C23646-B29C-469C-957E-D3B9E8AA3E83Q24613810-76688F65-6A10-459F-8F8A-7EFCB936626EQ24634669-CDAAA541-BFE0-4C24-A41D-DFF06B5CA486Q24654006-E5461ED0-507C-4438-8048-98D95565552CQ24671334-947A87FC-7D77-4B99-81EB-939E8B1A3100Q24685646-E787891F-FEF2-4186-9C39-1FA42C47A3A3Q28082393-ED2DF49B-E87F-43AF-B1AD-5AA35A478251Q28205561-D35B5975-CDD0-4E07-83A0-C6D1038A9890Q28740295-98EAD259-16EC-4E9E-853D-83CAFFE9E334Q28742048-BDEBB124-3ED2-45BB-95BF-C472B3DA22C1Q29619206-26126C94-C6DC-468A-8B19-9A3039A74B09Q30307704-66133D1E-9608-4385-A83D-B81536326A82Q31045942-EEDF0327-04D4-4B9C-A137-BA60E8EAFA4CQ33258856-F6457670-D52A-4535-819A-25978DD6ABCAQ33402481-4343E724-2AFB-4E65-8621-DB0469FFDED8Q33483729-E79FB498-3882-4ACF-96FC-47E80D9481BEQ33575005-9B9E8215-2FEB-4ABC-AE4E-7CF96FAB72D8Q33583058-FD63CC05-0EEE-4EE7-8DC8-F922E31E97BDQ33679883-85F93F9A-6962-4190-98B5-03A18D6A8C38Q33680045-49382A8A-977C-47CD-844A-24564E9F0F94Q33733232-61CD6857-662A-496C-8D94-E2CB0B8A863FQ33759046-4A95F206-BA68-48DB-ACDE-7FF6F721A82DQ33813997-38D29F8F-500D-4622-A80A-4362B3490868Q33916338-ABBCF3BF-3170-440F-BE10-080EF636F28AQ33918898-6D56A6CB-2321-44C4-98CC-889C9BE980B3Q33931174-F69821AE-F321-44B6-A5E1-369D137B9A88Q34004470-D8CA7264-6924-467F-81AB-046CDFBF3D9AQ34066238-04748CA6-10D4-42D5-B1F2-0E026ACE4C72Q34077480-21DAAEC1-4F1E-4384-B732-847AD32EB582Q34156001-D75AADEA-082A-4CED-8647-5AF8711C89C6Q34156208-6B69D9F6-9F7B-4DC0-AF2B-316A8C2CBBA7Q34252517-10D80391-E878-4702-909E-3682175D4B3BQ34283507-CC39D08E-7C6E-495E-A29C-8B698D207D98Q34385154-79BE467F-4232-4180-ACFC-10EC15941F79Q34385458-BF8021E1-931A-46A0-A63C-C52D3E787A0FQ34503694-9F70C62A-1394-4372-B0F0-DC54410C2851
P2860
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Localization of a susceptibili ...... and targeted linkage analysis
@ast
Localization of a susceptibili ...... and targeted linkage analysis
@en
Localization of a susceptibili ...... and targeted linkage analysis
@nl
type
label
Localization of a susceptibili ...... and targeted linkage analysis
@ast
Localization of a susceptibili ...... and targeted linkage analysis
@en
Localization of a susceptibili ...... and targeted linkage analysis
@nl
prefLabel
Localization of a susceptibili ...... and targeted linkage analysis
@ast
Localization of a susceptibili ...... and targeted linkage analysis
@en
Localization of a susceptibili ...... and targeted linkage analysis
@nl
P2093
P50
P3181
P356
P1433
P1476
Localization of a susceptibili ...... and targeted linkage analysis
@en
P2093
Björkqvist AM
Hemminki A
Järvinen H
Knuutila S
Salovaara R
Sistonen P
de la Chapelle A
P2860
P2888
P3181
P356
10.1038/NG0197-87
P407
P577
1997-01-01T00:00:00Z