about
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivoLoss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneityThe Gordon Wilson Lecture: The clinical legacy of Jonathan Hutchinson (1828-1913): syndromology and dysmorphology meet genomicsMicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cellsRecent progress in pancreatic cancerGermline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancersGermline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteriaGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilitySTK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreasGenetic alterations in pancreatic carcinomaClinical and molecular features of young-onset colorectal cancerColorectal cancer risk in hamartomatous polyposis syndromesSomatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanomaLKB1 associates with Brg1 and is necessary for Brg1-induced growth arrestNovel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor genemTOR and cancer therapyLKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domainLocalization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysisEnergy sensing pathways: Bridging type 2 diabetes and colorectal cancer?Screening for Pancreatic Cancer.High risk factors of pancreatic carcinoma.Update on our investigation of malignant tumors associated with Peutz-Jeghers syndrome in Japan.Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer.AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.Molecular technology and pancreatic cancer.Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia.Mutations in STK11 gene in Czech Peutz-Jeghers patientsFamily history and the risk of gastric cancer.Pancreatic adenocarcinoma: epidemiology and genetics.Peutz-Jeghers syndromeHigh prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.Multifocal Jejuno-ileal carcinoma in a 7-year-old boy with Peutz-Jeghers syndrome: A rare occurenceRisk of pancreatic cancer in families with Lynch syndrome.Hereditary hamartomatous polyposis syndromes: understanding the disease risks as children reach adulthood.Inherited predisposition to pancreatic cancer.Hereditary colorectal cancer: risk assessment and management.Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposisA novel mutation in STK11 gene is associated with Peutz-Jeghers syndrome in Chinese patients.Epidemiology of pancreatic cancer and the role of family historyInduction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.
P2860
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P2860
description
1987 nî lūn-bûn
@nan
1987 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Increased risk of cancer in the Peutz-Jeghers syndrome.
@ast
Increased risk of cancer in the Peutz-Jeghers syndrome.
@en
Increased risk of cancer in the Peutz-Jeghers syndrome.
@nl
type
label
Increased risk of cancer in the Peutz-Jeghers syndrome.
@ast
Increased risk of cancer in the Peutz-Jeghers syndrome.
@en
Increased risk of cancer in the Peutz-Jeghers syndrome.
@nl
prefLabel
Increased risk of cancer in the Peutz-Jeghers syndrome.
@ast
Increased risk of cancer in the Peutz-Jeghers syndrome.
@en
Increased risk of cancer in the Peutz-Jeghers syndrome.
@nl
P2093
P1476
Increased risk of cancer in the Peutz-Jeghers syndrome.
@en
P2093
Giardiello FM
Gittelsohn AM
Hamilton SR
Offerhaus GJ
Yardley JH
P304
P356
10.1056/NEJM198706113162404
P407
P577
1987-06-01T00:00:00Z