Purification, characterization, and biosynthesis of human acid ceramidase
about
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermisInvolvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formationCeramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphateOverexpression of acid ceramidase protects from tumor necrosis factor-induced cell deathAdvances in the discovery of N-acylethanolamine acid amidase inhibitorsA review of ceramide analogs as potential anticancer agentsPurification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinaseMolecular analysis of acid ceramidase deficiency in patients with Farber diseaseThe reverse activity of human acid ceramidaseHuman acid ceramidase: processing, glycosylation, and lysosomal targetingN-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cellsBiochemical and mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase inhibitionMolecular cloning, sequencing, and expression of the gene encoding alkaline ceramidase from Pseudomonas aeruginosa. Cloning of a ceramidase homologue from Mycobacterium tuberculosisTowards a human repertoire of monocytic lysosomal proteins.Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins.Overexpression and mass spectrometry analysis of mature human acid ceramidase.Cloning and characterization of a wheat neutral ceramidase gene Ta-CDase.Sphingosine 1-phosphate signalling in mammalian cells.Discovery and evaluation of inhibitors of human ceramidase.Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain.Acid ceramidase maintains the chondrogenic phenotype of expanded primary chondrocytes and improves the chondrogenic differentiation of bone marrow-derived mesenchymal stem cellsAcid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expressionAcid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.Intracellular sphingosine releases calcium from lysosomes.Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.Molecular targeting of acid ceramidase: implications to cancer therapy.Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins.Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice.Therapeutic applications of bioactive sphingolipids in hematological malignancies.Lysosomal lipid storage diseases.Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.Ceramidases, roles in sphingolipid metabolism and in health and disease.Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse.Autoproteolytic cleavage and activation of human acid ceramidase.A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.Purification and biochemical characterization of membrane-bound neutral ceramidase from camel brain (Camelus dromedarius).New insights on the use of desipramine as an inhibitor for acid ceramidase.Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.
P2860
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P2860
Purification, characterization, and biosynthesis of human acid ceramidase
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Purification, characterization, and biosynthesis of human acid ceramidase
@ast
Purification, characterization, and biosynthesis of human acid ceramidase
@en
Purification, characterization, and biosynthesis of human acid ceramidase
@nl
type
label
Purification, characterization, and biosynthesis of human acid ceramidase
@ast
Purification, characterization, and biosynthesis of human acid ceramidase
@en
Purification, characterization, and biosynthesis of human acid ceramidase
@nl
prefLabel
Purification, characterization, and biosynthesis of human acid ceramidase
@ast
Purification, characterization, and biosynthesis of human acid ceramidase
@en
Purification, characterization, and biosynthesis of human acid ceramidase
@nl
P2093
P356
P1476
Purification, characterization, and biosynthesis of human acid ceramidase
@en
P2093
E H Schuchman
K Bernardo
K Sandhoff
R J Desnick
P304
P356
10.1074/JBC.270.19.11098
P407
P577
1995-05-12T00:00:00Z