Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer - Wikidata - wikimedia - TriplyDB

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer

http://www.wikidata.org/entity/Q28305955

about

Epigenetic changes of DNA repair genes in cancer Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer Epigenetic regulation of DNA repair machinery in Helicobacter pylori-induced gastric carcinogenesis Epigenetic reduction of DNA repair in progression to gastrointestinal cancer Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis Prioritizing cancer-related genes with aberrant methylation based on a weighted protein-protein interaction network.DNA methyltransferases, DNA damage repair, and cancer Reduced syncytin-1 expression levels in placental syndromes correlates with epigenetic hypermethylation of the ERVW-1 promoter region.Small molecule inhibition of cytoskeletal dynamics in melanoma tumors results in altered transcriptional expression patterns of key genes involved in tumor initiation and progression.Effect of UVB irradiation on microRNA expression in mouse epidermis Clinical Significance of Peroxisome Proliferator-Activated Receptor γ and TRAP220 in Patients with Operable Colorectal Cancer.Baicalin modulates microRNA expression in UVB irradiated mouse skin.Epigenetics and colorectal cancer pathogenesis The Roles of the Methyl-CpG Binding Proteins in Cancer.Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases.Expression and role of nuclear receptor coregulators in colorectal cancer.The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update.

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P2860

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer

http://www.wikidata.org/entity/Q28305955

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Epigenetic downregulation of t ...... colorectal and ovarian cancer

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Epigenetic downregulation of t ...... colorectal and ovarian cancer

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Epigenetic downregulation of t ...... colorectal and ovarian cancer

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type

label

Epigenetic downregulation of t ...... colorectal and ovarian cancer

@ast

Epigenetic downregulation of t ...... colorectal and ovarian cancer

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Epigenetic downregulation of t ...... colorectal and ovarian cancer

@nl

prefLabel

Epigenetic downregulation of t ...... colorectal and ovarian cancer

@ast

Epigenetic downregulation of t ...... colorectal and ovarian cancer

@en

Epigenetic downregulation of t ...... colorectal and ovarian cancer

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Cancer Biology and Therapy

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Epigenetic downregulation of t ...... colorectal and ovarian cancer

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Alfonso Bellacosa

http://www.w3.org/2001/XMLSchema#string

Amar Majmundar

http://www.w3.org/2001/XMLSchema#string

Andrew Godwin

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Andrew Midzak

http://www.w3.org/2001/XMLSchema#string

Andrey Frolov

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Ashley Stewart

http://www.w3.org/2001/XMLSchema#string

Ching-Wei D Tzeng

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J Harrison Howard

http://www.w3.org/2001/XMLSchema#string

J Pablo Arnoletti

http://www.w3.org/2001/XMLSchema#string

Martin Heslin

http://www.w3.org/2001/XMLSchema#string

P2860

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity

Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis

The thymine DNA glycosylase MBD4 represses transcription and is associated with methylated p16(INK4a) and hMLH1 genes

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

CpG island methylator phenotype in colorectal cancer

Lessons from hereditary colorectal cancer

Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

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94-100

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4902248

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10.4161/CBT.8.1.7469

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19127118

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