DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
about
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cellsThe human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cellsDNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding propertiesKARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity.The gene for severe combined immunodeficiency disease in Athabascan-speaking Native Americans is located on chromosome 10p.Nonhomologous end joining and V(D)J recombination require an additional factorSaccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathwaysGene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8Chromosomal double-strand break repair in Ku80-deficient cellsModeling the study of DNA damage responses in miceMutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiaeA short C-terminal domain of Yku70p is essential for telomere maintenance.The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance.The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisPreventing Damage Limitation: Targeting DNA-PKcs and DNA Double-Strand Break Repair Pathways for Ovarian Cancer TherapyThe catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cellsGenomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP)Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationThe XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinaseRole of DNA-dependent protein kinase catalytic subunit in cancer development and treatmentAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionPhenylbutyrate attenuates the expression of Bcl-X(L), DNA-PK, caveolin-1, and VEGF in prostate cancer cellsGeneration of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleasesIdentification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol ANF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responsesRad51 expression and localization in B cells carrying out class switch recombinationInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsA mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells.Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.Replication protein A is sequentially phosphorylated during meiosis.hBRAG, a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved in the regulation of recombination activating gene 1 (RAG1).Functional analysis of human replication protein A in nucleotide excision repair.Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20Production of human monoclonal antibodies in SCID mouse.DNA-Dependent protein kinase is not required for efficient lentivirus integrationCharacterization of retrovirus-host DNA junctions in cells deficient in nonhomologous-end joiningEvidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway.Deletion of PKBalpha/Akt1 affects thymic developmentOf men in mice: the success and promise of humanized mouse models for human malaria parasite infections.
P2860
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P2860
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@ast
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@en
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@nl
type
label
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@ast
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@en
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@nl
prefLabel
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@ast
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@en
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@nl
P2093
P2860
P356
P1433
P1476
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
@en
P2093
C U Kirchgessner
M A Oettinger
P2860
P304
P356
10.1126/SCIENCE.7855601
P407
P577
1995-02-01T00:00:00Z