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Identification of Sef, a novel modulator of FGF signalling

Identification of Sef, a novel modulator of FGF signalling

http://www.wikidata.org/entity/Q28312228

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Biology of recently discovered cytokines: interleukin-17--a unique inflammatory cytokine with roles in bone biology and arthritis Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1 IL-17RC: a partner in IL-17 signaling and beyond Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish Structure and signalling in the IL-17 receptor family Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers Fibroblast growth factor signaling in the vasculature Kidney regeneration: common themes from the embryo to the adult The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor Evolution of the IL17 receptor family in chordates: a new subfamily IL17REL Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1 Differential gene expression in vertebrate embryos Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains Promotion and attenuation of FGF signaling through the Ras-MAPK pathway Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity A fully automated robotic system for microinjection of zebrafish embryos Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signaling Coordinating ERK/MAPK signalling through scaffolds and inhibitors Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.Generation of FGF reporter transgenic zebrafish and their utility in chemical screens.Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner ear.Regulated tissue fluidity steers zebrafish body elongation.Lef1 regulates Dusp6 to influence neuromast formation and spacing in the zebrafish posterior lateral line primordium.Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity Sef is a negative regulator of fiber cell differentiation in the ocular lens.Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system.Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway.The prepattern transcription factor Irx2, a target of the FGF8/MAP kinase cascade, is involved in cerebellum formation.Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.Ras/MAPK signaling from endomembranes The Fibroblast Growth Factor signaling pathway Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain Fibroblast growth factors in cancer: therapeutic possibilities.Tumor necrosis factor receptor 2 (TNFR2)·interleukin-17 receptor D (IL-17RD) heteromerization reveals a novel mechanism for NF-κB activation.Global analysis of hematopoietic and vascular endothelial gene expression by tissue specific microarray profiling in zebrafish.

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P2860

Identification of Sef, a novel modulator of FGF signalling

http://www.wikidata.org/entity/Q28312228

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Identification of Sef, a novel modulator of FGF signalling

@ast

Identification of Sef, a novel modulator of FGF signalling

@en

Identification of Sef, a novel modulator of FGF signalling

@nl

type

label

Identification of Sef, a novel modulator of FGF signalling

@ast

Identification of Sef, a novel modulator of FGF signalling

@en

Identification of Sef, a novel modulator of FGF signalling

@nl

prefLabel

Identification of Sef, a novel modulator of FGF signalling

@ast

Identification of Sef, a novel modulator of FGF signalling

@en

Identification of Sef, a novel modulator of FGF signalling

@nl

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Nature Cell Biology

P1476

Identification of Sef, a novel modulator of FGF signalling

@en

P2093

Robert Friesel

http://www.w3.org/2001/XMLSchema#string

Tetsuhiro Kudoh

http://www.w3.org/2001/XMLSchema#string

P2860

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

Ligand-independent activation of fibroblast growth factor receptors by point mutations in the extracellular, transmembrane, and kinase domains

Effective targeted gene 'knockdown' in zebrafish

Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch

A gene expression screen in zebrafish embryogenesis.

cDNA cloning and developmental expression of fibroblast growth factor receptors from Xenopus laevis

Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer.

Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling.

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165-9

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scholarly article

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10.1038/NCB749

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1001741289

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11802164

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