Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. - Wikidata - wikimedia - TriplyDB

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.

http://www.wikidata.org/entity/Q33478364

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Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Small molecule tools for functional interrogation of protein tyrosine phosphatases ZebraBeat: a flexible platform for the analysis of the cardiac rate in zebrafish embryos Zebrafish small molecule screens: Taking the phenotypic plunge Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development A chemical screen to identify novel inhibitors of fin regeneration in zebrafish Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus Zebrafish models of Tauopathy Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure Lef1 regulates Dusp6 to influence neuromast formation and spacing in the zebrafish posterior lateral line primordium.In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase.Controlling destiny through chemistry: small-molecule regulators of cell fate.Development of automated imaging and analysis for zebrafish chemical screens Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.Cytokine (IL16) and tyrphostin actions on ovarian primordial follicle development.The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries.A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads.Hydrogen peroxide primes heart regeneration with a derepression mechanism.ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice 15 years of zebrafish chemical screening Small molecule screening in zebrafish: swimming in potential drug therapies.Gene bionetworks that regulate ovarian primordial follicle assembly A manual small molecule screen approaching high-throughput using zebrafish embryos.Aldosterone modulates thiazide-sensitive sodium chloride cotransporter abundance via DUSP6-mediated ERK1/2 signaling pathway.Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia.A new strategy to ERADicate HER2-positive breast tumors?From phenotype to mechanism after zebrafish small molecule screens.Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age.In situ hybridization assay-based small molecule screening in zebrafish.Chemical screening in zebrafish for novel biological and therapeutic discovery.Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway Generation and application of signaling pathway reporter lines in zebrafish DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.Development of high-content assays for kidney progenitor cell expansion in transgenic zebrafish.Heart genetics in a small package, exploiting the condensed genome of Ciona intestinalis.Combating Adaptation to Cyclic Stretching By Prolonging Activation of Extracellular Signal-Regulated Kinase.

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Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.

http://www.wikidata.org/entity/Q33478364

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Zebrafish chemical screening r ...... expands cardiac cell lineages.

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Zebrafish chemical screening r ...... expands cardiac cell lineages.

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Zebrafish chemical screening r ...... expands cardiac cell lineages.

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Nature Chemical Biology

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Zebrafish chemical screening r ...... expands cardiac cell lineages.

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Ahmet Bakan

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Billy W Day

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Gabriela Molina

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Michael Tsang

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Pierre Queiroz de Oliveira

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Thomas E Smithgall

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Wade Znosko

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Weixiang Dai

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P2860

Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases

Crystal structure of the catalytic domain of human MAP kinase phosphatase 5: structural insight into constitutively active phosphatase

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

Structural genomics of protein phosphatases

Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

Development and validation of a genetic algorithm for flexible docking

Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase

A role for MKP3 in axial patterning of the zebrafish embryo

Promotion and attenuation of FGF signaling through the Ras-MAPK pathway

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10.1038/NCHEMBIO.190

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