Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
about
From the chemistry of epoxy-sugar nucleosides to the discovery of anti-HIV agent 4'-ethynylstavudine-Festinavir4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitroHybridization properties of 4'-branched oligonucleotides.Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitroDevelopment of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compoundsSynthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents.Potential of 4'-C-substituted nucleosides for the treatment of HIV-1.4'-modified nucleoside analogs: potent inhibitors active against entecavir-resistant hepatitis B virus.Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.Fluorinated Nucleosides: Synthesis and Biological ImplicationMechanism of inhibition of HIV-1 reverse transcriptase by 4'-Ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor.Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.A review of methods to synthesise 4'-substituted nucleosides.Synthesis and antiviral activity of apio dideoxy nucleosides with azido or amino substituent.First synthesis and anti-HIV evaluation of 4'-methyl-cyclopentanyl 9-deazaadenosine.Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides.Synthesis and Anti-HIV Activity of Novel 4'-Trifluoromethylated 5'-Deoxycarbocyclic Nucleoside Phosphonic Acids.Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants.A proposed structure of modified nucleosides expected to have high antiviral activity and low toxicity.Chemical stability of 4'-azidocytidine and its prodrug balapiravir.Synthesis and antiviral evaluation of novel 4'-hydroxymethyl branched apiosyl nucleosides.Synthesis and anti-HIV activity of 4'-cyano-2',3'-didehydro-3'-deoxythymidine.Synthesis and antiviral evaluation of 4'-alkoxy analogues of 9-(beta-D-xylofuranosyl)adenine.Novel synthesis and anti-HIV activity of 4'-branched exomethylene carbocyclic nucleosides using a ring-closing metathesis of triene.Efficient synthesis of 4'-cyclopropylated carbovir analogues with use of ring-closing metathesis from glycolate.Synthesis of (+/-)-4'-ethynyl and 4'-cyano carbocyclic analogues of stavudine (d4T).Synthetic use of epoxy-sugar nucleosides.Synthesis of 4'-Methoxy 2'-Deoxynucleoside Phosphoramidites for Incorporation into Oligonucleotides.
P2860
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P2860
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@ast
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@en
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@nl
type
label
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@ast
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@en
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@nl
prefLabel
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@ast
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@en
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@nl
P2093
P356
P1476
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
@en
P2093
D Crawford-Ruth
E J Prisbe
J P Verheyden
M J McRoberts
R M Rydzewski
P304
P356
10.1021/JM00086A013
P407
P577
1992-04-17T00:00:00Z