Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity - Wikidata - wikimedia - TriplyDB

Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity

Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity

http://www.wikidata.org/entity/Q28365676

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A unique error signature for human DNA polymerase nu Sequence determination of nucleic acids containing 5-methylisocytosine and isoguanine: identification and insight into polymerase replication of the non-natural nucleobases Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.Replication through an abasic DNA lesion: structural basis for adenine selectivity Solution Structure, Mechanism of Replication, and Optimization of an Unnatural Base Pair Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase Structures of KOD and 9°N DNA polymerases complexed with primer template duplex Structure and function of an RNA-reading thermostable DNA polymerase Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota Conformational dynamics of Thermus aquaticus DNA polymerase I during catalysis.Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.Optimization of an unnatural base pair toward natural-like replication Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.Synthesis and evaluation of new spacers for use as dsDNA end-caps Dependence of DNA polymerase replication rate on external forces: a model based on molecular dynamics simulations Unnatural substrate repertoire of A, B, and X family DNA polymerases.Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase.The expanded genetic alphabet.Minor groove hydrogen bonds and the replication of unnatural base pairs Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766.Fluorophore-quencher pair for monitoring protein motion.An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides Neighbouring bases in template influence base-pairing of isoguanine In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism.Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus.dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.A mechanism of nucleotide misincorporation during transcription due to template-strand misalignment.Selective transcription of an unnatural naphthyridine:imidazopyridopyrimidine base pair containing four hydrogen bonds with T7 RNA polymerase.A pre-equilibrium before nucleotide binding limits fingers subdomain closure by Klentaq1.The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases.Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.NTP-driven translocation by human RNA polymerase II.Crystal structures of ternary complexes of archaeal B-family DNA polymerases.

P2860

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P2860

Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity

http://www.wikidata.org/entity/Q28365676

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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2001 թվականի հունիսին հրատարակված գիտական հոդված

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2001年の論文

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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Crystal structures of a ddATP- ...... incorporation and selectivity

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G Waksman

http://www.w3.org/2001/XMLSchema#string

Y Li

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P2860

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

Improved methods for building protein models in electron density maps and the location of errors in these models

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

DNA polymerases: structural diversity and common mechanisms

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