Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.
about
A unique error signature for human DNA polymerase nuSubstitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin,Kinetic analysis of the unique error signature of human DNA polymerase ν.Testing computational prediction of missense mutation phenotypes: functional characterization of 204 mutations of human cystathionine beta synthaseDistinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection.DNA replication fidelity.Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta.Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon.The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination.Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion.Dividing the workload at a eukaryotic replication fork.Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase.Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766.Fidelity of the human mitochondrial DNA polymerase.Comparative kinetics of nucleotide analog incorporation by vent DNA polymerase.The R- and S-diastereoisomeric effects on the guanidinohydantoin-induced mutations in DNA.The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics.Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases.Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.The nature of the transition mismatches with Watson-Crick architecture: the G*·T or G·T* DNA base mispair or both? A QM/QTAIM perspective for the biological problem.The physicochemical essence of the purine·pyrimidine transition mismatches with Watson-Crick geometry in DNA: A·C* versa A*·C. A QM and QTAIM atomistic understanding.
P2860
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P2860
Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2002 թվականի փետրվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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Discrimination against purine- ...... e I: a structural explanation.
@ast
Discrimination against purine- ...... e I: a structural explanation.
@en
Discrimination against purine- ...... e I: a structural explanation.
@nl
type
label
Discrimination against purine- ...... e I: a structural explanation.
@ast
Discrimination against purine- ...... e I: a structural explanation.
@en
Discrimination against purine- ...... e I: a structural explanation.
@nl
prefLabel
Discrimination against purine- ...... e I: a structural explanation.
@ast
Discrimination against purine- ...... e I: a structural explanation.
@en
Discrimination against purine- ...... e I: a structural explanation.
@nl
P2093
P2860
P356
P1476
Discrimination against purine- ...... e I: a structural explanation.
@en
P2093
Catherine M Joyce
Dana T Minnick
Lixing Liu
Nigel D F Grindley
Thomas A Kunkel
P2860
P304
P356
10.1073/PNAS.032457899
P407
P577
2002-02-01T00:00:00Z