Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
about
Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922)Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytesFunctional profiling of a human cytomegalovirus genomeA novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products.Potent antiviral activity of an antisense oligonucleotide complementary to the intron-exon boundary of human cytomegalovirus genes UL36 and UL37Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinantHuman cytomegalovirus: challenges, opportunities and new drug developmentSilencing disease genes in the laboratory and the clinicInterplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus.Treatments for choroidal and retinal neovascularization: a focus on oligonucleotide therapy and delivery for the regulation of gene function.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.DNA as therapeutics; an update.RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences.Gene therapy for infectious diseasesHuman cytomegalovirus terminase as a target for antiviral chemotherapy.Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA.Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression.RNA as a target for developing antivirals.Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.Cytomegalovirus-mediated induction of antisense mRNA expression to UL44 inhibits virus replication in an astrocytoma cell line: identification of an essential gene.Stably expressed antisense RNA to cytomegalovirus UL83 inhibits viral replication.Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotidesHuman cytomegalovirus DNA replication: antiviral targets and drugs.Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): DNA viruses.Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.Chemical modification of oligonucleotides for therapeutic, bioanalytical and other applications.Clinical aspects of cytomegalovirus antiviral resistance in solid organ transplant recipients.Inhibition of high affinity basic fibroblast growth factor binding by oligonucleotides.Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression.Antisense antimicrobial therapeuticsPre-mRNA mis-splicing of sarcomeric genes in heart failure.Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment.NC-mediated nucleolar localization of retroviral gag proteins.New cell-based indicator assays for the detection of human cytomegalovirus infection and screening of inhibitors of viral immediate-early 2 protein activity.The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein.Human cytomegalovirus infection decreases expression of thrombospondin-1 independent of the tumor suppressor protein p53.Glucose conjugation of anti-HIV-1 oligonucleotides containing unmethylated CpG motifs reduces their immunostimulatory activity.Neural retina limits the nonviral gene transfer to retinal pigment epithelium in an in vitro bovine eye model.Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein BTreatment of cytomegalovirus retinitis: A growing number of options.
P2860
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P2860
Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
description
1993 nî lūn-bûn
@nan
1993 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Antiviral activity of a phosph ...... s major immediate-early region
@ast
Antiviral activity of a phosph ...... s major immediate-early region
@en
Antiviral activity of a phosph ...... s major immediate-early region
@nl
type
label
Antiviral activity of a phosph ...... s major immediate-early region
@ast
Antiviral activity of a phosph ...... s major immediate-early region
@en
Antiviral activity of a phosph ...... s major immediate-early region
@nl
prefLabel
Antiviral activity of a phosph ...... s major immediate-early region
@ast
Antiviral activity of a phosph ...... s major immediate-early region
@en
Antiviral activity of a phosph ...... s major immediate-early region
@nl
P2093
P2860
P356
P1476
Antiviral activity of a phosph ...... s major immediate-early region
@en
P2093
P2860
P304
P356
10.1128/AAC.37.9.1945
P407
P577
1993-09-01T00:00:00Z