Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation
about
Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphateAn orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus ChallengeRole of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet.Current and potential treatments for ubiquitous but neglected herpesvirus infectionsBrincidofovir (CMX001) inhibits BK polyomavirus replication in primary human urothelial cellsMechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activityHydroxyurea potentiates the antiherpesvirus activities of purine and pyrimidine nucleoside and nucleoside phosphonate analogsVaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infectionsCharacterization of the DNA- and dNTP-binding activities of the human cytomegalovirus DNA polymerase catalytic subunit UL54.The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization.N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors.Selective inhibition of human papillomavirus-induced cell proliferation by (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosineResistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and managementPotent antiviral activity of north-methanocarbathymidine against Kaposi's sarcoma-associated herpesvirus.Development of CMX001 for the Treatment of Poxvirus Infections.Human cytomegalovirus resistance to deoxyribosylindole nucleosides maps to a transversion mutation in the terminase subunit-encoding gene UL89.Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action.Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections.Glycoprotein targeted therapeutics: a new era of anti-herpes simplex virus-1 therapeuticsSelection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme.Antiviral evaluation of octadecyloxyethyl esters of (S)-3-hydroxy-2-(phosphonomethoxy)propyl nucleosides against herpesviruses and orthopoxviruses.Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymeraseCidofovir Activity against Poxvirus Infections.Disposition of the acyclic nucleoside phosphonate (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine.Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragmentsActivities of different classes of acyclic nucleoside phosphonates against BK virus in primary human renal cells.Alpha interferon augments cidofovir's antiviral and antiproliferative activities.Cidofovir inhibits genome encapsidation and affects morphogenesis during the replication of vaccinia virus.Analysis of Mutations in the Gene Encoding Cytomegalovirus DNA Polymerase in a Phase 2 Clinical Trial of Brincidofovir Prophylaxis.N-1 regioselective Michael-type addition of 5-substituted uracils to (2-hydroxyethyl) acrylate.Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand.
P2860
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P2860
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Effect of incorporation of cid ...... A polymerase on DNA elongation
@ast
Effect of incorporation of cid ...... A polymerase on DNA elongation
@en
Effect of incorporation of cid ...... A polymerase on DNA elongation
@nl
type
label
Effect of incorporation of cid ...... A polymerase on DNA elongation
@ast
Effect of incorporation of cid ...... A polymerase on DNA elongation
@en
Effect of incorporation of cid ...... A polymerase on DNA elongation
@nl
prefLabel
Effect of incorporation of cid ...... A polymerase on DNA elongation
@ast
Effect of incorporation of cid ...... A polymerase on DNA elongation
@en
Effect of incorporation of cid ...... A polymerase on DNA elongation
@nl
P2093
P2860
P356
P1476
Effect of incorporation of cid ...... A polymerase on DNA elongation
@en
P2093
P2860
P304
P356
10.1128/AAC.41.3.594
P407
P577
1997-03-01T00:00:00Z