PDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathways - Wikidata - wikimedia - TriplyDB

PDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathways

PDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathways

http://www.wikidata.org/entity/Q28395353

about

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications Effects of a novel phosphodiesterase 10A inhibitor in non-human primates: A therapeutic approach for schizophrenia with improved side effect profile Pharmacological characterization of a novel potent, selective, and orally active phosphodiesterase 10A inhibitor, PDM-042 [(E)-4-(2-(2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)vinyl)-6-(pyrrolidin-1-yl)pyrimidin-4-yl)morpholine] in rats: pot Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity.

P2860

Q26753116-22BE2C0D-B9E7-4C24-BE5A-CD775EFCC101 Q28389666-BDFB9F22-E68C-40BC-999A-F0D660837725 Q37591807-C644B0D3-CBE7-4B1A-9AFA-188979FC6EF2 Q39819933-C4FE3456-EC42-4D17-AFDE-7D834C488E39

P2860

PDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathways

http://www.wikidata.org/entity/Q28395353

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@ast

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@en

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@nl

type

label

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@ast

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@en

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@nl

prefLabel

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@ast

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@en

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@nl

P1433

Q28395353-B0EBF77B-5766-4C68-9F46-6335827DEC84

P1476

Q28395353-60A4D891-2F45-4605-8600-73A127B7D5EA

P2093

Q28395353-1AFDD9F7-141B-4C51-9351-B9A488DE7BAD

Q28395353-57002B71-C6D9-4B1F-8658-3D1326912707

Q28395353-6757B878-86A7-4300-B481-1DCCA897E73F

Q28395353-A9366587-29A2-4CC6-888C-DC18B3D6E6DA

Q28395353-C134A348-9218-4EB8-9B77-91D10C72BCD6

Q28395353-EB35CD9C-4329-40B5-ADED-FEF4400BCDB9

P2860

Q28395353-061BE469-E7AC-4E40-A2EF-16C85298C221

Q28395353-0ECA462A-09DF-4115-BD08-4B4669D4DDA6

Q28395353-14152284-78C1-4035-91D1-005606FC8DBC

Q28395353-16AA56A3-A466-4537-A64C-6E679CE40585

Q28395353-1DC4B268-2FA2-4BA4-ADAF-45D119041101

Q28395353-2345266A-766B-4058-B734-658712417352

Q28395353-23476305-3C7D-44E6-B3E5-0F2E34E20AFA

Q28395353-2724BB52-B9D0-4E8B-86AC-838D6E0334F5

Q28395353-38A194BE-705B-4135-8C6E-7DCDE305DE3C

Q28395353-3EE38874-8F6F-44FB-93F9-4412C837CD03

P304

Q28395353-5E3BA861-7D3F-47ED-9422-A8517CF3848F

P31

Q28395353-86BC3B9E-4401-4369-9710-EFD78FB760D4

P3181

Q28395353-CEBCEA88-7689-4311-923C-B40127316448

P356

Q28395353-EECA0314-3BDB-4B04-B69B-33F5DF9694C4

P407

Q28395353-1160E98B-227A-4B28-84ED-B1A1F6E15A9C

P433

Q28395353-67F0CA9A-AFAC-45D9-BEED-856E24A30F86

P478

Q28395353-9B3D90E0-405F-4164-B084-D8A732DABE79

P577

Q28395353-E299DE7F-B6DA-47C4-B98A-7FFF6551E4A2

P5875

Q28395353-D8E7B47A-65A1-4F5B-B971-959817660E6C

P698

Q28395353-B2EA8EE2-46F5-4991-90C9-6CD8EC2FB56F

P921

Q28395353-C727C91E-5B16-4438-8EF4-A9C40BC609ED

P932

Q28395353-02B92004-56F3-438B-B055-8E0BC4BA1003

P3181

P356

P1433

Pharmacology research & perspectives

P1476

PDE10A inhibitors stimulate or ...... irect striatal output pathways

@en

P2093

Annemie L Y Wellens

http://www.w3.org/2001/XMLSchema#string

Anton A H P Megens

http://www.w3.org/2001/XMLSchema#string

Greet Vanhoof

http://www.w3.org/2001/XMLSchema#string

Herman M R Hendrickx

http://www.w3.org/2001/XMLSchema#string

Michel M A Mahieu

http://www.w3.org/2001/XMLSchema#string

Peter de Boer

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neurons

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

Parkinson's disease and D1 dopamine receptors

The full D1 dopamine receptor agonist SKF-82958 induces neuropeptide mRNA in the normosensitive striatum of rats: regulation of D1/D2 interactions by muscarinic receptors

Inhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating.

Inhibition of Phosphodiesterase 10A Increases the Responsiveness of Striatal Projection Neurons to Cortical Stimulation

Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization

Immunohistochemical localization of PDE10A in the rat brain

P304

e00057

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4781917

http://www.w3.org/2001/XMLSchema#string

P356

10.1002/PRP2.57

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P577

2014-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

264804909

http://www.w3.org/2001/XMLSchema#string

P698

25505601

http://www.w3.org/2001/XMLSchema#string

P921

corpus striatum

P932

4186443

http://www.w3.org/2001/XMLSchema#string