Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization
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Investigating striatal function through cell-type-specific manipulationsPDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathwaysCompromised NMDA/Glutamate Receptor Expression in Dopaminergic Neurons Impairs Instrumental Learning, But Not Pavlovian Goal Tracking or Sign Tracking(1,2,3)The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learningSeverely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons.Targeting neuronal populations of the striatumBiological substrates of addiction.Amphetamine-induced sensitization has little effect on multiple learning paradigms and fails to rescue mice with a striatal learning defect.Alcohol Elicits Functional and Structural Plasticity Selectively in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum.Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations.Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways).Genetic reconstruction of dopamine D1 receptor signaling in the nucleus accumbens facilitates natural and drug reward responses.Acetylcholine encodes long-lasting presynaptic plasticity at glutamatergic synapses in the dorsal striatum after repeated amphetamine exposure.NMDA Receptors on Dopaminoceptive Neurons Are Essential for Drug-Induced Conditioned Place Preference.Overinhibition of corticostriatal activity following prenatal cocaine exposure.Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants.Utility of genetically modified mice for understanding the neurobiology of substance use disorders.The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons.Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processesGluN1 deletions in D1- and A2A-expressing cell types reveal distinct modes of behavioral regulation.Striatopallidal Neuron NMDA Receptors Control Synaptic Connectivity, Locomotor, and Goal-Directed Behaviors.Adenosine 2A receptors modulate reward behaviours for methamphetamine.Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle.Activation of NMDA receptors leads to phosphorylation of TRPV1 S800 by protein kinase C and A-Kinase anchoring protein 150 in rat trigeminal ganglia.Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration.Development of sensitization to methamphetamine in offspring prenatally exposed to morphine, methadone and buprenorphine.Selective alterations of NMDAR function and plasticity in D1 and D2 medium spiny neurons in the nucleus accumbens shell following chronic intermittent ethanol exposure.The secretogranin II gene is a signal integrator of glutamate and dopamine inputs.Dopamine's Effects on Corticostriatal Synapses during Reward-Based Behaviors.
P2860
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P2860
Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization
description
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2011
@ast
im März 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/03/08)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/03/08)
@nl
наукова стаття, опублікована в березні 2011
@uk
name
Balanced NMDA receptor activit ...... for amphetamine sensitization
@ast
Balanced NMDA receptor activit ...... for amphetamine sensitization
@en
Balanced NMDA receptor activit ...... for amphetamine sensitization
@nl
type
label
Balanced NMDA receptor activit ...... for amphetamine sensitization
@ast
Balanced NMDA receptor activit ...... for amphetamine sensitization
@en
Balanced NMDA receptor activit ...... for amphetamine sensitization
@nl
prefLabel
Balanced NMDA receptor activit ...... for amphetamine sensitization
@ast
Balanced NMDA receptor activit ...... for amphetamine sensitization
@en
Balanced NMDA receptor activit ...... for amphetamine sensitization
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Balanced NMDA receptor activit ...... for amphetamine sensitization
@en
P2093
Lisa R Beutler
Nigel S Bamford
Richard D Palmiter
P2860
P304
P3181
P356
10.1073/PNAS.1101424108
P407
P577
2011-02-22T00:00:00Z