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Utrophin up-regulation by an artificial transcription factor in transgenic mice

Utrophin up-regulation by an artificial transcription factor in transgenic mice

http://www.wikidata.org/entity/Q28469278

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Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice.β1-syntrophin modulation by miR-222 in mdx mice.UtroUp is a novel six zinc finger artificial transcription factor that recognises 18 base pairs of the utrophin promoter and efficiently drives utrophin upregulation.High throughput screening in duchenne muscular dystrophy: from drug discovery to functional genomics Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function.Transcription factor rational design improves directed differentiation of human mesenchymal stem cells into skeletal myocytes.Upregulating endogenous genes by an RNA-programmable artificial transactivator.Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus.Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents RNA activation of haploinsufficient Foxg1 gene in murine neocortex.Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy Duchenne muscular dystrophy drug discovery - the application of utrophin promoter activation screening.Artificial Zinc-Finger Transcription Factor of A20 Suppresses Restenosis in Sprague Dawley Rats after Carotid Injury via the PPARα Pathway.Novel adeno-associated viral vector delivering the utrophin gene regulator jazz counteracts dystrophic pathology in mdx mice.Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.Enhancing Neuronogenesis and Counteracting Neuropathogenic Gene Haploinsufficiencies by RNA Gene Activation.ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA.

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

http://www.wikidata.org/entity/Q28469278

description

2007 nî lūn-bûn

@nan

2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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type

label

Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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prefLabel

Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Utrophin up-regulation by an artificial transcription factor in transgenic mice

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Agata Desantis

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Annalisa Onori

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Aristide Floridi

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Cinzia Severini

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Claudio Passananti

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Dilair Baban

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Elisabetta Mattei

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Georgios Strimpakos

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Kay E Davies

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Maria Grazia Di Certo

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P2860

Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

Design and selection of novel Cys2His2 zinc finger proteins

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

Designer zinc-finger proteins and their applications

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

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10.1371/JOURNAL.PONE.0000774

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6128375

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1942121

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